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Delftia tsuruhatensis Wiki2Web Clarity Challenge

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Study Guide: Delftia tsuruhatensis: Taxonomy, Pathogenesis, and Therapeutic Applications

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Delftia tsuruhatensis: Taxonomy, Pathogenesis, and Therapeutic Applications Study Guide

Taxonomy and Fundamental Characteristics

The bacterium *Delftia tsuruhatensis* is classified under the Domain Archaea, a group known for extremophiles.

Answer: False

Explanation: The source material explicitly classifies *Delftia tsuruhatensis* under the Domain Bacteria, not Archaea.

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*Delftia tsuruhatensis* belongs to the Kingdom Pseudomonadati, a classification used for a specific group of bacteria.

Answer: True

Explanation: The provided classification places *Delftia tsuruhatensis* within the Kingdom Pseudomonadati.

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The Phylum for *Delftia tsuruhatensis* is Firmicutes, which is a major phylum of Gram-positive bacteria.

Answer: False

Explanation: The source material identifies the Phylum for *Delftia tsuruhatensis* as Pseudomonadota, which consists of Gram-negative bacteria, not Firmicutes.

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*Delftia tsuruhatensis* is a member of the Class Betaproteobacteria, a diverse group of bacteria.

Answer: True

Explanation: The classification provided confirms that *Delftia tsuruhatensis* belongs to the Class Betaproteobacteria.

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The bacterium *Delftia tsuruhatensis* is classified within the Order Enterobacteriales.

Answer: False

Explanation: The source material states that *Delftia tsuruhatensis* is classified within the Order Burkholderiales, not Enterobacteriales.

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*Delftia tsuruhatensis* belongs to the Family Comamonadaceae, a family of Gram-negative bacteria.

Answer: True

Explanation: The provided classification confirms that *Delftia tsuruhatensis* is a member of the Family Comamonadaceae.

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The full species name of the bacterium discussed is *Delftia aeruginosa*.

Answer: False

Explanation: The full species name of the bacterium is *Delftia tsuruhatensis*, not *Delftia aeruginosa*.

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*Delftia tsuruhatensis* was first described by Shigematsu et al. in 2003.

Answer: True

Explanation: The source material explicitly states that *Delftia tsuruhatensis* was first described by Shigematsu et al. in 2003.

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*Delftia tsuruhatensis* is characterized as a Gram-positive, spherical, and non-motile bacterium.

Answer: False

Explanation: *Delftia tsuruhatensis* is characterized as a Gram-negative, rod-shaped, and motile bacterium, not Gram-positive, spherical, and non-motile.

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*Delftia tsuruhatensis* was initially isolated in 2003 from a hospital environment in Germany.

Answer: False

Explanation: *Delftia tsuruhatensis* was initially isolated in 2003 from a wastewater treatment plant in Japan, not a hospital environment in Germany.

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The cells of *Delftia tsuruhatensis* are typically observed in long chains.

Answer: False

Explanation: The cells of *Delftia tsuruhatensis* are typically observed singly or in pairs, not in long chains.

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Individual cells of *Delftia tsuruhatensis* measure approximately 0.7–1.2 micrometers in width and 2.4–4.0 micrometers in length.

Answer: True

Explanation: The source material specifies that individual cells of *Delftia tsuruhatensis* measure approximately 0.7–1.2 micrometers in width and 2.4–4.0 micrometers in length.

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The type strain information for *Delftia tsuruhatensis* identifies specific, preserved cultures that serve as the definitive reference standard for the species.

Answer: True

Explanation: The type strain information for *Delftia tsuruhatensis* indeed identifies specific, preserved cultures that function as the definitive reference standard for the species.

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The Gram-negative characteristic of *Delftia tsuruhatensis* means its cell wall retains crystal violet stain during the Gram staining procedure.

Answer: False

Explanation: The Gram-negative characteristic of *Delftia tsuruhatensis* signifies that its cell wall does not retain the crystal violet stain during the Gram staining procedure.

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Being catalase-positive means *Delftia tsuruhatensis* produces the enzyme catalase, which breaks down hydrogen peroxide.

Answer: True

Explanation: Being catalase-positive indicates that *Delftia tsuruhatensis* produces the enzyme catalase, which is responsible for breaking down hydrogen peroxide.

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*Delftia tsuruhatensis* is generally classified as a virus, a non-cellular infectious agent.

Answer: False

Explanation: *Delftia tsuruhatensis* is generally classified as a species of bacterium, not a virus.

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Being a motile bacterium means *Delftia tsuruhatensis* is capable of self-propulsion.

Answer: True

Explanation: Being a motile bacterium signifies that *Delftia tsuruhatensis* possesses the inherent capability for self-propulsion.

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At which taxonomic rank is *Delftia tsuruhatensis* classified as Bacteria?

Answer: Domain

Explanation: The highest taxonomic rank at which *Delftia tsuruhatensis* is classified as Bacteria is the Domain.

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Which Kingdom does *Delftia tsuruhatensis* belong to?

Answer: Pseudomonadati

Explanation: *Delftia tsuruhatensis* is classified under the Kingdom Pseudomonadati.

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What is the Phylum of *Delftia tsuruhatensis*?

Answer: Pseudomonadota

Explanation: The Phylum of *Delftia tsuruhatensis* is Pseudomonadota.

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To which Class is *Delftia tsuruhatensis* assigned?

Answer: Betaproteobacteria

Explanation: *Delftia tsuruhatensis* is assigned to the Class Betaproteobacteria.

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The Order that *Delftia tsuruhatensis* falls under is:

Answer: Burkholderiales

Explanation: *Delftia tsuruhatensis* is classified under the Order Burkholderiales.

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Which Family does *Delftia tsuruhatensis* belong to?

Answer: Comamonadaceae

Explanation: *Delftia tsuruhatensis* belongs to the Family Comamonadaceae.

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What is the Genus of the bacterium *Delftia tsuruhatensis*?

Answer: *Delftia*

Explanation: The Genus of the bacterium *Delftia tsuruhatensis* is *Delftia*.

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Who first described *Delftia tsuruhatensis* and in what year?

Answer: Shigematsu et al. in 2003

Explanation: *Delftia tsuruhatensis* was first described by Shigematsu et al. in 2003.

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Which of the following describes the key morphological characteristics of *Delftia tsuruhatensis*?

Answer: Gram-negative, rod-shaped, motile

Explanation: *Delftia tsuruhatensis* is characterized by its Gram-negative staining, rod-shaped morphology, and motility.

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From where was *Delftia tsuruhatensis* initially isolated?

Answer: A wastewater treatment plant in Japan

Explanation: *Delftia tsuruhatensis* was initially isolated from a wastewater treatment plant in Japan.

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What are the approximate dimensions of *Delftia tsuruhatensis* cells?

Answer: 0.7–1.2 micrometers in width and 2.4–4.0 micrometers in length

Explanation: Individual cells of *Delftia tsuruhatensis* measure approximately 0.7–1.2 micrometers in width and 2.4–4.0 micrometers in length.

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What is the purpose of the 'Type strain' information provided for *Delftia tsuruhatensis*?

Answer: To serve as the definitive reference standard for the species

Explanation: The 'Type strain' information for *Delftia tsuruhatensis* serves as the definitive reference standard for the species.

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What does it mean for *Delftia tsuruhatensis* to be 'catalase-positive' and 'oxidase-positive'?

Answer: It produces catalase (breaks down hydrogen peroxide) and cytochrome c oxidase (involved in electron transport chain).

Explanation: Being 'catalase-positive' means *Delftia tsuruhatensis* produces catalase to break down hydrogen peroxide, and 'oxidase-positive' means it produces cytochrome c oxidase, an enzyme in the electron transport chain.

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What is the general classification of *Delftia tsuruhatensis*?

Answer: A species of bacterium

Explanation: *Delftia tsuruhatensis* is generally classified as a species of bacterium.

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What is the significance of *Delftia tsuruhatensis* being a motile bacterium?

Answer: It signifies its capability of self-propulsion.

Explanation: The motility of *Delftia tsuruhatensis* signifies its inherent capability for self-propulsion.

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Pathogenic Profile and Clinical Significance

*Delftia tsuruhatensis* is identified as an opportunistic and emergent pathogen.

Answer: True

Explanation: The source material identifies *Delftia tsuruhatensis* as an opportunistic and emergent pathogen.

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All documented human infections caused by *Delftia tsuruhatensis* are community-acquired.

Answer: False

Explanation: All documented human infections caused by *Delftia tsuruhatensis* are healthcare-associated, not community-acquired.

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The fact that all documented human infections by *Delftia tsuruhatensis* are healthcare-associated suggests a particular risk in clinical environments.

Answer: True

Explanation: The observation that all documented human infections by *Delftia tsuruhatensis* are healthcare-associated strongly suggests a heightened risk in clinical environments, particularly for vulnerable patient populations.

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What is the pathogenic nature of *Delftia tsuruhatensis*?

Answer: An opportunistic and emergent pathogen

Explanation: *Delftia tsuruhatensis* is identified as an opportunistic and emergent pathogen.

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What is a notable characteristic of documented human infections involving *Delftia tsuruhatensis*?

Answer: All are healthcare-associated.

Explanation: A notable characteristic of documented human infections involving *Delftia tsuruhatensis* is that all are healthcare-associated.

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Why is it important that documented human infections by *Delftia tsuruhatensis* are healthcare-associated?

Answer: It indicates a particular risk in clinical environments for immunocompromised patients.

Explanation: The healthcare-associated nature of *Delftia tsuruhatensis* infections is important as it highlights a specific risk in clinical environments, particularly for immunocompromised patients.

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Environmental Bioremediation Potential

*Delftia tsuruhatensis* can degrade heavy metals like lead and mercury.

Answer: False

Explanation: *Delftia tsuruhatensis* is noted for its ability to degrade phenolic compounds and aniline, not heavy metals like lead and mercury.

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The ability of *D. tsuruhatensis* to degrade phenolic compounds and aniline suggests its potential in industrial solvent production.

Answer: False

Explanation: The ability of *D. tsuruhatensis* to degrade phenolic compounds and aniline suggests its potential applications in bioremediation, not industrial solvent production.

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The initial isolation of *Delftia tsuruhatensis* from a wastewater treatment plant suggests its adaptation to pristine, oligotrophic environments.

Answer: False

Explanation: The initial isolation of *Delftia tsuruhatensis* from a wastewater treatment plant suggests its adaptation to environments rich in organic matter and pollutants, rather than pristine, oligotrophic conditions.

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Which environmental pollutants can *Delftia tsuruhatensis* degrade?

Answer: Phenolic compounds and aniline

Explanation: *Delftia tsuruhatensis* is capable of degrading phenolic compounds and aniline.

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Why is the degradation of phenolic compounds and aniline by *D. tsuruhatensis* considered significant?

Answer: It suggests potential applications in bioremediation of pollutants.

Explanation: The degradation of phenolic compounds and aniline by *D. tsuruhatensis* is significant because it suggests potential applications in the bioremediation of these common and toxic pollutants.

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How does the initial isolation location of *Delftia tsuruhatensis* from a wastewater treatment plant inform its ecological role?

Answer: It indicates a role in environmental detoxification due to its ability to degrade pollutants.

Explanation: The initial isolation of *Delftia tsuruhatensis* from a wastewater treatment plant suggests its ecological role in environmental detoxification, consistent with its ability to degrade pollutants.

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Interactions with Quorum Sensing and Biofilms

*Delftia tsuruhatensis* promotes quorum sensing and enhances biofilm formation.

Answer: False

Explanation: *Delftia tsuruhatensis* inhibits quorum sensing and suppresses biofilm formation, rather than promoting them.

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The ability of *D. tsuruhatensis* to inhibit quorum sensing and biofilm formation suggests its potential for developing new therapeutic drugs.

Answer: True

Explanation: The capacity of *D. tsuruhatensis* to inhibit quorum sensing and biofilm formation indeed suggests its potential for the development of novel therapeutic agents.

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*Delftia tsuruhatensis* specifically inhibits quorum sensing and biofilm formation against *Staphylococcus aureus*.

Answer: False

Explanation: *Delftia tsuruhatensis* specifically inhibits quorum sensing and biofilm formation against *Pseudomonas aeruginosa*, not *Staphylococcus aureus*.

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The activities of *Delftia tsuruhatensis* increase *Pseudomonas aeruginosa*'s susceptibility to antibiotics by a factor of 2 to 3 times.

Answer: True

Explanation: The activities of *Delftia tsuruhatensis* have been shown to increase *Pseudomonas aeruginosa*'s susceptibility to antibiotics by a factor of 2 to 3 times.

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By inhibiting quorum sensing and suppressing biofilm formation, *Delftia tsuruhatensis* can make antibiotic-resistant bacteria more vulnerable to existing antibiotics.

Answer: True

Explanation: By inhibiting quorum sensing and suppressing biofilm formation, *Delftia tsuruhatensis* can indeed enhance the vulnerability of antibiotic-resistant bacteria to existing antibiotics.

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Quorum sensing is a bacterial communication system that allows bacteria to coordinate gene expression based on nutrient availability.

Answer: False

Explanation: Quorum sensing is a bacterial communication system that allows bacteria to coordinate gene expression based on population density, not nutrient availability.

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Biofilms are structured communities of bacterial cells that are easily penetrated by antibiotics.

Answer: False

Explanation: Biofilms are structured communities of bacterial cells that can shield bacteria from antibiotics, making them difficult to penetrate.

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How does *Delftia tsuruhatensis* interact with quorum sensing and biofilm formation?

Answer: It inhibits quorum sensing and suppresses biofilm formation.

Explanation: *Delftia tsuruhatensis* inhibits quorum sensing and suppresses biofilm formation.

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What potential therapeutic application is suggested by *D. tsuruhatensis*'s biofilm interactions?

Answer: Source for developing new therapeutic drugs to combat antibiotic-resistant bacteria

Explanation: The biofilm interactions of *D. tsuruhatensis* suggest its potential as a source for developing new therapeutic drugs to combat antibiotic-resistant bacteria.

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Against which specific pathogen does *Delftia tsuruhatensis* inhibit quorum sensing and biofilm formation?

Answer: *Pseudomonas aeruginosa*

Explanation: *Delftia tsuruhatensis* specifically inhibits quorum sensing and biofilm formation against *Pseudomonas aeruginosa*.

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What effect does *Delftia tsuruhatensis*'s activity have on *Pseudomonas aeruginosa*'s susceptibility to antibiotics?

Answer: It increases susceptibility by a factor of 2 to 3 times.

Explanation: The activity of *Delftia tsuruhatensis* increases *Pseudomonas aeruginosa*'s susceptibility to antibiotics by a factor of 2 to 3 times.

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In what way could *Delftia tsuruhatensis* contribute to the fight against antibiotic resistance?

Answer: By making antibiotic-resistant bacteria more vulnerable to existing antibiotics.

Explanation: *Delftia tsuruhatensis* could contribute to combating antibiotic resistance by rendering antibiotic-resistant bacteria more vulnerable to existing antibiotics.

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What is quorum sensing, and how does *Delftia tsuruhatensis* interfere with it?

Answer: It's a bacterial communication system based on population density; *Delftia tsuruhatensis* interferes with this process.

Explanation: Quorum sensing is a bacterial communication system regulated by population density, and *Delftia tsuruhatensis* interferes with this process.

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Why is the inhibition of biofilms by *Delftia tsuruhatensis* important in a medical context?

Answer: Biofilms can shield bacteria from antibiotics and the host immune system.

Explanation: The inhibition of biofilms by *Delftia tsuruhatensis* is medically important because biofilms can protect bacteria from antibiotics and the host immune system, making infections more challenging to treat.

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Anti-Malarial Efficacy and Vector Control

In 2023, a discovery published in *Nature* showed *Delftia tsuruhatensis* prevents malaria development in mosquitoes.

Answer: False

Explanation: The discovery regarding *Delftia tsuruhatensis*'s role in preventing malaria development in mosquitoes was published in the journal *Science* in 2023, not *Nature*.

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Mosquitoes infected by *Delftia tsuruhatensis* showed a 75% reduction in the number of *Plasmodium* oocysts.

Answer: True

Explanation: Mosquitoes infected by *Delftia tsuruhatensis* indeed demonstrated a 75% reduction in the number of *Plasmodium* oocysts.

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Mosquitoes infected with *D. tsuruhatensis* exhibited malaria infection rates that were double those of uninfected mosquitoes.

Answer: False

Explanation: Mosquitoes infected with *D. tsuruhatensis* exhibited malaria infection rates that were one-third those of uninfected mosquitoes, indicating a significant reduction, not a doubling.

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*Delftia tsuruhatensis* secretes the compound quinine to prevent malaria development in mosquitoes.

Answer: False

Explanation: *Delftia tsuruhatensis* secretes harmane to prevent malaria development in mosquitoes, not quinine.

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The genus *Serratia* is mentioned as another type of bacteria that can be genetically modified to prevent malaria.

Answer: True

Explanation: The source material indicates that the genus *Serratia* can be genetically modified to prevent malaria.

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The genus *Wolbachia* is noted for its application in controlling cholera.

Answer: False

Explanation: The genus *Wolbachia* is noted for its application in controlling dengue, not cholera.

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The secretion of harmane by *Delftia tsuruhatensis* directly leads to a 75% increase in *Plasmodium* oocysts within infected mosquitoes.

Answer: False

Explanation: The secretion of harmane by *Delftia tsuruhatensis* leads to a 75% *reduction* in *Plasmodium* oocysts, not an increase.

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The broader implication of *Delftia tsuruhatensis*'s role in preventing malaria is that it could serve as a natural biological control agent.

Answer: True

Explanation: The broader implication of *Delftia tsuruhatensis*'s role in preventing malaria is indeed its potential to serve as a natural biological control agent.

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*Delftia tsuruhatensis* naturally secretes harmane to prevent malaria, while *Serratia* is genetically modified for a similar outcome.

Answer: True

Explanation: The source material differentiates that *Delftia tsuruhatensis* naturally secretes harmane for malaria prevention, whereas *Serratia* can be genetically modified for a similar purpose.

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What significant discovery regarding *Delftia tsuruhatensis* was published in *Science* in 2023?

Answer: Its ability to prevent malaria development in mosquitoes

Explanation: A significant discovery published in *Science* in 2023 highlighted *Delftia tsuruhatensis*'s ability to prevent malaria development in mosquitoes.

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How does *Delftia tsuruhatensis* impact the number of *Plasmodium* oocysts in infected mosquitoes?

Answer: It leads to a 75% reduction in oocysts.

Explanation: *Delftia tsuruhatensis* leads to a 75% reduction in the number of *Plasmodium* oocysts in infected mosquitoes.

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What was the observed difference in malaria infection rates between mosquitoes infected with *D. tsuruhatensis* and uninfected mosquitoes?

Answer: Infected mosquitoes had one third the infection rates.

Explanation: Mosquitoes infected with *D. tsuruhatensis* exhibited malaria infection rates that were one-third those of uninfected mosquitoes.

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What compound does *Delftia tsuruhatensis* secrete to prevent malaria development in mosquitoes?

Answer: Harmane

Explanation: *Delftia tsuruhatensis* secretes the compound harmane to prevent malaria development in mosquitoes.

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Which other genus of bacteria is mentioned as being genetically modified to prevent malaria?

Answer: *Serratia*

Explanation: The genus *Serratia* is mentioned as another type of bacteria that can be genetically modified to prevent malaria.

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Which genus of bacteria is noted for its use in controlling dengue?

Answer: *Wolbachia*

Explanation: The genus *Wolbachia* is noted for its application in controlling dengue.

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How does the secretion of harmane by *Delftia tsuruhatensis* specifically affect *Plasmodium* oocysts?

Answer: It leads to a 75% reduction in their number.

Explanation: The secretion of harmane by *Delftia tsuruhatensis* specifically leads to a 75% reduction in the number of *Plasmodium* oocysts.

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What is the broader implication of *Delftia tsuruhatensis*'s role in preventing malaria development in mosquitoes?

Answer: It could serve as a natural biological control agent for malaria transmission.

Explanation: The broader implication of *Delftia tsuruhatensis*'s role in preventing malaria development in mosquitoes is its potential as a natural biological control agent for malaria transmission.

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How does *Delftia tsuruhatensis* compare to *Serratia* in terms of malaria prevention strategies?

Answer: *Delftia tsuruhatensis* naturally secretes harmane, while *Serratia* can be genetically modified to prevent malaria.

Explanation: *Delftia tsuruhatensis* naturally secretes harmane to prevent malaria, whereas *Serratia* can be genetically modified for a similar outcome.

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What is the distinction between *Delftia tsuruhatensis*'s application and *Wolbachia*'s use in disease control?

Answer: *Delftia tsuruhatensis* prevents malaria, while *Wolbachia* controls dengue.

Explanation: *Delftia tsuruhatensis* is involved in preventing malaria, while *Wolbachia* is utilized for controlling dengue.

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