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Endoscopic mucosal resection Wiki2Web Clarity Challenge

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Study Guide: Endoscopic Mucosal Resection (EMR): Principles, Techniques, and Applications

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Endoscopic Mucosal Resection (EMR): Principles, Techniques, and Applications Study Guide

Introduction to Endoscopic Mucosal Resection (EMR)

Gastroenterology is the medical specialty most closely linked with the practice of Endoscopic Mucosal Resection.

Answer: True

Explanation: Gastroenterologists specialize in the diagnosis and treatment of diseases of the digestive system, making them the primary practitioners of endoscopic procedures like EMR.

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EMR is a technique for removing the mucous membrane lining, known as a mucosectomy.

Answer: True

Explanation: Endoscopic Mucosal Resection (EMR) is indeed a specific method for performing a mucosectomy, which is the surgical removal of the mucous membrane lining.

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What is Endoscopic Mucosal Resection (EMR)?

Answer: A minimally invasive endoscopic method for removing superficial lesions in the digestive tract.

Explanation: EMR is a minimally invasive endoscopic technique specifically designed for the removal of superficial cancerous or abnormal lesions found within the digestive tract.

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Which medical field is most commonly associated with performing Endoscopic Mucosal Resection?

Answer: Gastroenterology

Explanation: Gastroenterology is the medical specialty most closely associated with EMR, as gastroenterologists are experts in the diagnosis and endoscopic treatment of digestive system disorders.

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What is the primary goal of Endoscopic Mucosal Resection (EMR)?

Answer: To remove cancerous or abnormal lesions from the digestive tract minimally invasively.

Explanation: The primary goal of EMR is the minimally invasive removal of cancerous or abnormal superficial lesions within the digestive tract, preserving the integrity of the deeper layers.

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Indications and Patient Selection for EMR

The main objective of EMR is the complete removal of all types of tumors within the digestive tract, regardless of their depth.

Answer: False

Explanation: The primary objective of EMR is the removal of *superficial* lesions. It is not suitable for tumors that have invaded deeply into the digestive tract wall.

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EMR is recommended for early esophageal cancers that have spread to lymph nodes.

Answer: False

Explanation: EMR is indicated for early esophageal cancers that are superficial and confined to the mucosal layer, not for those that have metastasized to lymph nodes.

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The prognosis after EMR for early esophageal cancer is generally considered worse than traditional surgical methods.

Answer: False

Explanation: The prognosis for patients undergoing EMR for early esophageal cancers is comparable to that of traditional surgical resection, indicating similar favorable outcomes.

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EMR is suitable for esophageal tumors that are differentiated, slightly raised, and measure less than 2 centimeters in diameter.

Answer: True

Explanation: EMR is considered appropriate for differentiated, slightly raised esophageal tumors under 2 cm, or differentiated and ulcerated tumors under 1 cm, provided there is no evidence of lymph node or distant metastasis.

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EMR is used in managing Barrett's esophagus to treat dysplastic or malignant polypoid lesions.

Answer: True

Explanation: EMR is a valuable tool for managing Barrett's esophagus by enabling the removal of dysplastic or early malignant polypoid lesions that arise in this condition.

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EMR and submucosal dissection are effective for superficial colorectal cancers (stage T1a).

Answer: True

Explanation: EMR and endoscopic submucosal dissection are highly effective for resecting superficial colorectal cancers, specifically those classified as stage T1a, which have invaded only the uppermost layer of the submucosa.

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EMR is primarily indicated for early esophageal cancers confined to the submucosa layer.

Answer: False

Explanation: EMR is indicated for early esophageal cancers confined to the innermost mucosal layer, not for those invading the submucosa, which represents deeper penetration.

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EMR is considered a highly effective method for removing large, non-malignant colorectal polyps.

Answer: True

Explanation: EMR is highly effective for the resection of large, non-malignant polyps in the colon and rectum, offering a less invasive alternative to surgery.

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EMR is particularly advocated for which type of early esophageal cancer?

Answer: Superficial cancers confined only to the innermost mucosal lining.

Explanation: EMR is specifically advocated for early esophageal cancers that are superficial and limited to the mucosal layer, as deeper invasion requires more extensive treatment modalities.

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According to the source, how does the prognosis after EMR for early esophageal cancer compare to traditional surgery?

Answer: Prognosis is comparable to surgical resection.

Explanation: The prognosis for patients undergoing EMR for early esophageal cancers is comparable to that of traditional surgical resection, indicating similar favorable outcomes with potentially less invasiveness.

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EMR and submucosal dissection are considered highly effective for which type of colorectal lesions?

Answer: Large, non-malignant polyps and superficially invasive (T1a) cancers.

Explanation: EMR and endoscopic submucosal dissection are highly effective for treating large, non-malignant polyps and colorectal cancers that are superficial, specifically those classified as stage T1a.

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EMR Techniques and Methodologies

Endoscopic Mucosal Resection (EMR) is a minimally invasive endoscopic technique used for removing superficial lesions within the digestive tract.

Answer: True

Explanation: EMR is an endoscopic procedure, not a surgical one involving external incisions. It is designed for the removal of superficial lesions from the lining of the digestive tract.

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The 'strip biopsy' method for EMR involves using a laser to cut the lesion from the esophageal wall.

Answer: False

Explanation: The strip biopsy method for EMR utilizes endoscopic tools like forceps and a snare for resection, often with electrocautery, but does not involve the use of a laser.

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In the strip biopsy technique, saline is injected submucosally to help the lesion protrude.

Answer: True

Explanation: Submucosal injection of saline is a key step in the strip biopsy technique, creating a cushion that elevates the lesion for easier grasping and resection.

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The double-snare polypectomy method is indicated for deeply invasive, protruding lesions.

Answer: False

Explanation: The double-snare polypectomy method is indicated for protruding lesions, not for those that are deeply invasive.

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The 'band and snare' technique, also known as 'suck and cut,' relies on aspirating the lesion into a cap before resection.

Answer: True

Explanation: The 'band and snare' or 'suck and cut' technique utilizes a cap attached to the endoscope to aspirate the lesion, which is then resected with a snare.

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The primary function of injecting saline during EMR is to numb the tissue before resection.

Answer: False

Explanation: The primary function of injecting saline during EMR is to create a submucosal cushion that separates the mucosa from the underlying layers, causing the lesion to protrude and facilitating resection, not to numb the tissue.

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Electrocautery is used in EMR mainly for visualizing the lesion margins.

Answer: False

Explanation: Electrocautery in EMR is primarily used for cutting tissue, resecting the lesion, and controlling bleeding by sealing blood vessels, not for visualizing margins.

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The 'strip biopsy' method for EMR typically involves all the following steps EXCEPT:

Answer: Using a laser to precisely cut around the lesion.

Explanation: The strip biopsy method involves submucosal injection, marking the border, and resection with forceps and snare, but it does not utilize a laser for cutting.

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What is the purpose of injecting saline into the submucosa during certain EMR techniques?

Answer: To create a cushion that separates the mucosa and causes the lesion to protrude.

Explanation: Injecting saline into the submucosa during EMR creates a fluid cushion that elevates the mucosal lesion, separating it from the underlying layers and facilitating its safe removal.

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The 'band and snare' technique, also known as 'suck and cut,' utilizes which key component?

Answer: A clear cap attached to the endoscope.

Explanation: The 'band and snare' or 'suck and cut' technique employs a clear cap fitted onto the endoscope, which is used to aspirate the lesion into the cap before resection with a snare.

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Which technique involves using a snare to strangulate and resect the lesion after it has been lifted or trapped?

Answer: Strip biopsy, double-snare, or cap-assisted methods.

Explanation: Various EMR techniques, including strip biopsy, double-snare polypectomy, and cap-assisted methods, utilize a snare to strangulate and resect the lesion after it has been lifted or trapped.

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What is the role of electrocautery in EMR?

Answer: To cut tissue, resect the lesion, and control bleeding.

Explanation: Electrocautery plays a critical role in EMR by enabling the cutting and resection of tissue, as well as providing hemostasis by sealing blood vessels during the procedure.

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Which statement accurately describes the resection process in the saline/epinephrine injection EMR method?

Answer: A high-frequency scalpel excises mucosa outside the border, and a snare resects the lifted lesion.

Explanation: In the saline/epinephrine injection method, a scalpel is used to excise mucosa around the lesion's border after submucosal injection, and then a snare is used to resect the elevated lesion.

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The 'double-snare polypectomy' method is specifically indicated for what type of lesion?

Answer: Protruding lesions.

Explanation: The double-snare polypectomy method is specifically indicated for protruding lesions, where a snare can effectively grasp and resect the lesion.

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Complications, Management, and Outcomes of EMR

After EMR, the resected tissue is discarded without further analysis.

Answer: False

Explanation: The resected tissue from EMR is submitted for microscopic examination to assess factors such as invasion depth and resection margins.

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The ulcer formed after an EMR procedure typically takes about six weeks to heal.

Answer: False

Explanation: The ulcer resulting from an EMR procedure typically heals within approximately three weeks, not six.

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A German study reported that over 25% of patients undergoing EMR for Barrett's esophagus experienced bleeding complications.

Answer: False

Explanation: A preliminary German report indicated that 12.5% of patients experienced bleeding complications after EMR for Barrett's esophagus, not over 25%.

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Postoperative bleeding after EMR can be managed by injecting clips or using electrocautery.

Answer: True

Explanation: Postoperative bleeding following EMR can be effectively managed using endoscopic techniques such as injecting epinephrine, applying clips, or utilizing electrocautery to achieve hemostasis.

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The 'nonlifting sign' after submucosal injection suggests EMR is safe to proceed without issue.

Answer: False

Explanation: The 'nonlifting sign' is a contraindication for EMR, suggesting potential adherence to deeper layers and an increased risk of complications, rather than indicating safety.

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If an EMR perforation is recognized immediately, surgery is always the first line of treatment.

Answer: False

Explanation: If an EMR perforation is recognized immediately, the initial management is typically endoscopic closure with clips; surgery is considered if endoscopic closure is unsuccessful.

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The recurrence rate for esophageal squamous cell carcinoma after EMR is typically between 10% and 20%.

Answer: False

Explanation: The recurrence rate for esophageal squamous cell carcinoma after EMR is reported to range from 0% to 8%, not between 10% and 20%.

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For large, non-invasive colorectal polyps, EMR is generally more expensive than surgical resection.

Answer: False

Explanation: For large, non-invasive colorectal polyps, EMR is generally considered less expensive and safer than surgical resection.

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Strictures, bleeding, and perforation are the main potential complications associated with EMR.

Answer: True

Explanation: The primary potential complications following EMR include bleeding, perforation of the digestive tract, and the development of strictures (narrowing).

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Why is the microscopic examination of the resected tissue crucial after EMR?

Answer: To assess the depth of invasion, resection margins, and vascular involvement.

Explanation: Microscopic examination of the resected specimen is crucial for pathology assessment, determining the depth of tumor invasion, evaluating the completeness of the resection (margins), and identifying any vascular or lymphatic involvement.

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Approximately how long does it usually take for the ulcer resulting from EMR to heal?

Answer: Approximately 3 weeks

Explanation: The ulcer that forms at the site of resection following an EMR procedure typically heals within approximately three weeks.

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According to a preliminary German report on EMR for Barrett's esophagus, what percentage of patients experienced bleeding complications?

Answer: 12.5%

Explanation: A preliminary German report indicated that 12.5% of patients experienced bleeding complications after EMR for Barrett's esophagus, which were managed endoscopically.

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How can postoperative bleeding after EMR be managed?

Answer: By injecting epinephrine, using coagulation, or applying clips.

Explanation: Postoperative bleeding following EMR can be effectively managed using endoscopic techniques such as injecting diluted epinephrine, applying clips to the bleeding site, or using electrocautery.

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What is the recommended preventive measure against postoperative hemorrhage following EMR?

Answer: Administration of acid-reducing medications.

Explanation: To help prevent postoperative hemorrhage after EMR, administration of acid-reducing medications is recommended to decrease stomach acid production and protect the healing site.

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If a perforation is recognized immediately after an EMR procedure, what is the initial recommended management?

Answer: Attempt closure using endoscopic clips.

Explanation: If an EMR perforation is recognized immediately, the initial management is typically endoscopic closure with clips; surgery is considered if endoscopic closure is unsuccessful.

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Compared to surgical resection for large, non-invasive colorectal polyps, EMR is generally considered:

Answer: Less expensive and safer.

Explanation: For large, non-invasive colorectal polyps, EMR is generally considered less expensive and safer compared to surgical resection.

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What is a potential consequence of EMR if the mucosa is not adequately lifted from the underlying layers during the procedure?

Answer: Increased risk of perforation.

Explanation: If the mucosa is not adequately lifted during EMR, the risk of perforating the digestive tract wall increases, as the instruments may inadvertently engage deeper layers.

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Clinical Practice and Proficiency in EMR

A Mayo Clinic study suggested that proficiency in EMR requires performing approximately 100 procedures.

Answer: True

Explanation: According to a study by the Mayo Clinic group, achieving proficiency in performing Endoscopic Mucosal Resection requires approximately 100 procedures.

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What does the source suggest about the availability of high-volume colorectal EMR procedures in the United States?

Answer: Many centers in the US now offer them.

Explanation: The source indicates that many centers across the United States now offer high-quality, high-volume colorectal EMR procedures.

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