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Epidemiology of HIV/AIDS Wiki2Web Clarity Challenge

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Study Guide: The Global HIV/AIDS Pandemic: Epidemiology, Regional Dynamics, and Response

Cheat Sheet:
The Global HIV/AIDS Pandemic: Epidemiology, Regional Dynamics, and Response Study Guide

Epidemiology and Global Burden

As of 2024, the global HIV/AIDS pandemic has resulted in an estimated 73.4 million to 116.4 million confirmed cases and over 44 million deaths worldwide.

Answer: True

Explanation: As of 2024, the global HIV/AIDS pandemic has led to an estimated 73.4 million to 116.4 million confirmed cases and 44.1 million deaths worldwide.

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The global incidence of HIV infection peaked in 2005, after which it began a rapid decline.

Answer: False

Explanation: The global incidence of HIV infection peaked in 1997, not 2005, and then fell rapidly to about 2.6 million per year by 2005.

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From 2010 to 2020, the incidence of HIV decreased by 23%, primarily due to significant progress in Western Europe and North America.

Answer: False

Explanation: From 2010 to 2020, the incidence of HIV decreased by 23%, but this progress was predominantly driven by significant decreases in Eastern Africa and Southern Africa, not Western Europe and North America.

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According to the World Health Organization (WHO), approximately how many people globally were infected with HIV by 2023?

Answer: 39 million

Explanation: According to the World Health Organization (WHO), approximately 39 million people globally were infected with HIV by 2023.

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In which year did the global incidence of HIV infection reach its peak?

Answer: 1997

Explanation: The 2015 Global Burden of Disease Study estimated that the global incidence of HIV infection peaked in 1997.

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What was the estimated number of new HIV cases reported worldwide in 2018?

Answer: 1.7 million

Explanation: In 2018, approximately 1.7 million new cases of HIV were reported worldwide.

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Origins and Historical Context

The HIV virus is believed to have originated in non-human primates in Central Africa, with initial transfers to humans occurring primarily in the mid-20th century.

Answer: False

Explanation: The source indicates that the initial transfers of HIV from non-human primates to humans occurred during the late 19th or early 20th century, not primarily in the mid-20th century.

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The first outbreak of HIV/AIDS was recognized in 1981, and HIV was identified as its cause two years later.

Answer: True

Explanation: The first outbreak of HIV/AIDS was recognized on June 5, 1981, and the Human Immunodeficiency Virus (HIV) was identified as its cause in 1983, two years later.

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HIV-1 group M, the strain most responsible for the global epidemic, is genetically reconstructed to have originated in Kinshasa around 1920.

Answer: True

Explanation: Genetic history reconstruction suggests that HIV-1 group M, the strain responsible for the global epidemic, may have originated in Kinshasa around 1920.

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Regional Dynamics: Sub-Saharan Africa

In Sub-Saharan Africa, young women aged 15 to 24 years are twice as likely as men of the same age to be living with HIV.

Answer: True

Explanation: In Sub-Saharan Africa, young women aged 15 to 24 years are indeed twice as likely as men of the same age to be living with HIV.

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South Africa has the largest population of people living with HIV globally, with a prevalence rate of 13.9% in 2022.

Answer: True

Explanation: South Africa has the largest population of people living with HIV globally, with 8.45 million individuals, and a prevalence rate of 13.9% as of 2022.

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Which region accounts for two-thirds of the global incidence of HIV?

Answer: Africa Region

Explanation: The Africa Region accounts for two-thirds of the global incidence of HIV.

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Which of the following is NOT listed as a facilitating factor in HIV transmission in Sub-Saharan Africa, beyond sexual contact?

Answer: Routine childhood vaccinations

Explanation: Routine childhood vaccinations are not listed as a facilitating factor in HIV transmission in Sub-Saharan Africa. Other factors include STDs, scarification, unsafe blood transfusions, and poor hygiene/nutrition.

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What impact did AIDS-denialist policies in South Africa have on the epidemic?

Answer: They led to several hundred thousand unnecessary deaths.

Explanation: AIDS-denialist policies in South Africa significantly hindered the distribution of antiretroviral drugs and are estimated to have led to several hundred thousand unnecessary deaths.

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Regional Dynamics: Asia and Oceania

The Middle East and North Africa (MENA) region has the highest HIV/AIDS prevalence rate globally due to increasing new infections.

Answer: False

Explanation: The Middle East and North Africa (MENA) region has the lowest HIV/AIDS prevalence rate globally, estimated at less than 0.1% between 1990 and 2018.

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In South and South-East Asia, the HIV epidemic is largely concentrated among specific groups like injecting drug users and sex workers.

Answer: True

Explanation: In South and South-East Asia, the HIV epidemic is largely concentrated among specific groups including injecting drug users, men who have sex with men, sex workers, and their clients.

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Thailand is the only East Asian country with an HIV prevalence over 1%, and its rate has been increasing since 2001.

Answer: False

Explanation: Thailand is the only East Asian country with an HIV prevalence over 1%, but its rate has declined from 1.7% in 2001 to 1.1% in 2015, not increased.

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What is the estimated HIV/AIDS prevalence among the adult population (15-49) in the Middle East and North Africa (MENA) region?

Answer: Less than 0.1%

Explanation: The HIV/AIDS prevalence among the adult population (15-49) in the Middle East and North Africa (MENA) region is estimated at less than 0.1%.

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In Metro Manila, Philippines, what accounted for the majority of new HIV infections according to a surveillance study?

Answer: Sexual contact between males

Explanation: A surveillance study in Metro Manila, Philippines, found that sexual contact between males accounted for the majority of new HIV infections.

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What is the national HIV prevalence level in East Asia among adults aged 15-49?

Answer: 0.1%

Explanation: The national HIV prevalence level in East Asia among adults aged 15-49 is low, at 0.1%.

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Which country in East Asia is noted for having an HIV prevalence over 1%?

Answer: Thailand

Explanation: Thailand is the only East Asian country noted for having an HIV prevalence over 1%.

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Regional Dynamics: The Americas and Europe

In 2019, approximately 1.2 million people in the United States had HIV, and the majority of them were unaware of their infection.

Answer: False

Explanation: In 2019, approximately 1.2 million people in the United States had HIV, but only 13% of them were unaware of their infection, meaning the majority were aware.

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The Caribbean is the second-most affected region in the world by HIV/AIDS, but has seen a significant decrease in new infections and deaths since 2010.

Answer: True

Explanation: The Caribbean is indeed the second-most affected region globally by HIV/AIDS, and it has experienced a significant decrease in new infections and deaths since 2010.

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In Central and South America, Guatemala and Honduras are the only countries with national HIV prevalence rates exceeding 1%.

Answer: True

Explanation: In Central and South America, only Guatemala and Honduras are noted as having national HIV prevalence rates exceeding 1%.

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The number of new HIV/AIDS cases in the United States began to decline in 1996, marking the first such decrease since the epidemic's onset.

Answer: True

Explanation: The number of new HIV/AIDS cases in the United States began to decline in 1996, which was the first year of such a decrease since the epidemic's onset.

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In 2016, HIV/AIDS prevalence was increasing most rapidly among Indigenous Canadians.

Answer: True

Explanation: In 2016, HIV/AIDS prevalence was indeed increasing most rapidly among Indigenous Canadians, who accounted for 11.3% of new infections that year.

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Eastern Europe and Central Asia are experiencing a rapidly growing HIV epidemic, largely due to increased intravenous drug use and a rise in sex workers.

Answer: True

Explanation: Eastern Europe and Central Asia are experiencing a rapidly growing HIV epidemic, with the infection rate increasing due to factors such as increased intravenous drug use and a rise in sex workers.

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What percentage of people living with HIV in Western Europe and North America had suppressed viral loads in 2020?

Answer: 67%

Explanation: In 2020, 67% of people living with HIV in Western Europe and North America had suppressed viral loads.

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What is the primary route of HIV transmission in the Caribbean, accounting for two-thirds of AIDS cases?

Answer: Heterosexual intercourse

Explanation: HIV transmission in the Caribbean largely occurs through heterosexual intercourse, accounting for two-thirds of AIDS cases in the region.

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What is the highest HIV prevalence rate within the Caribbean region?

Answer: The Bahamas (3.2%)

Explanation: Within the Caribbean, The Bahamas has the highest HIV prevalence, with 3.2% of its adult population affected.

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In Central and South America, what is the approximate ratio of HIV-infected men to HIV-infected women in countries with prevalence rates over 1%?

Answer: 3:1

Explanation: In Central and South American countries with HIV prevalence rates over 1%, HIV-infected men outnumber HIV-infected women by a ratio of approximately 3:1.

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As of 2016, what percentage of people over age 13 living with HIV in the US were unaware of their infection?

Answer: 14%

Explanation: In 2016, 14% of the 1.1 million people over age 13 living with HIV in the US were unaware of their infection.

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Which U.S. region had the highest population rates of persons diagnosed with HIV infection per 100,000 people in 2015?

Answer: South

Explanation: In 2015, the U.S. South region had the highest population rates of persons diagnosed with HIV infection per 100,000 people.

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What was the estimated number of people living with HIV/AIDS in Canada in 2016?

Answer: 63,100

Explanation: In 2016, approximately 63,100 people were estimated to be living with HIV/AIDS in Canada.

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Prevention, Treatment, and Research

Despite advancements in mRNA technology, developing an HIV vaccine is challenging due to the virus's significantly greater number of variants compared to other viruses like COVID-19.

Answer: True

Explanation: The greatest challenge in developing an HIV vaccine, even with mRNA technology, is the virus's significantly greater number of variants that an effective vaccine would need to address.

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What is Canada's goal for HIV/AIDS elimination by 2030, based on the UNAIDS 90-90-90 strategy?

Answer: 90% of those positive know their status, 90% diagnosed receive treatment, 90% on treatment achieve viral suppression.

Explanation: Canada aims to achieve the UNAIDS 90-90-90 strategy goals by 2030, which means 90% of those positive know their status, 90% diagnosed receive treatment, and 90% on treatment achieve viral suppression.

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What is the current status regarding a cure for HIV/AIDS?

Answer: There is no available cure for HIV/AIDS to this day.

Explanation: To this day, there is no available cure for HIV/AIDS, although major efforts in containment and improved anti-viral therapy have yielded positive results.

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Social and Transmission Factors

The most frequent mode of HIV transmission in the United States is through heterosexual contact, with women being the most affected demographic.

Answer: False

Explanation: The most frequent mode of HIV transmission in the United States is through male homosexual sexual relations, with gay and bisexual men being the most affected demographic.

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African Americans are disproportionately affected by HIV/AIDS in the United States, accounting for nearly half of the total HIV-positive population.

Answer: True

Explanation: African Americans are significantly disproportionately affected by HIV/AIDS in the United States, making up about 48% of the total HIV-positive population.

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UNAIDS suggests that transgender people are at the highest risk of acquiring HIV, with a 30 times higher risk compared to other populations.

Answer: False

Explanation: UNAIDS suggests that sex workers are at the highest risk of acquiring HIV (30 times higher), while transgender people have a 13 times higher risk compared to other populations.

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What percentage of new HIV diagnoses in the United States in 2014 were accounted for by gay and bisexual men?

Answer: 67%

Explanation: Gay and bisexual men accounted for 67% of total estimated new HIV diagnoses in the United States in 2014.

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