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Haplogroup Q-M242 is primarily defined by the M346 single-nucleotide polymorphism (SNP).
Answer: False
Explanation: While M346 is a significant SNP in the lineage leading to Haplogroup Q-M242, the primary defining mutation for Haplogroup Q-M242 itself is the M242 SNP, as indicated by its nomenclature and confirmed in genetic studies. M346 is an ancestral haplogroup marker.
Haplogroup Q-M242 is one of the two major subclades branching from Haplogroup P1.
Answer: True
Explanation: Haplogroup P1 is the ancestral haplogroup from which two major Y-DNA haplogroups diverged: Haplogroup Q-M242 and Haplogroup R-M207. Both are significant in terms of global distribution and population genetics.
The M242 SNP, defining Haplogroup Q-M242, was discovered by Luigi Cavalli-Sforza and colleagues.
Answer: False
Explanation: The M242 SNP was discovered by Mark Seielstad and colleagues in 2003, not Luigi Cavalli-Sforza and his team.
Q1/Q-L472 and Q2/Q-L275 are the two primary subclades of Haplogroup Q-M242.
Answer: True
Explanation: Haplogroup Q-M242 is characterized by two main subclades: Q1 (which includes Q-L472 and Q-MEH2) and Q2 (which includes Q-L275). These represent the primary branches of this haplogroup.
The 'Q*' designation in distribution data refers to samples belonging to Haplogroup Q that do not fit into defined subclades.
Answer: True
Explanation: The 'Q*' designation is typically used in population genetics studies to denote samples belonging to Haplogroup Q but which do not match any of the currently defined, specific subclades. This often occurs in regions with limited detailed analysis or unique genetic variations.
The Y Chromosome Consortium (YCC) is one of the main sources for Haplogroup Q-M242 phylogenetic trees.
Answer: True
Explanation: The Y Chromosome Consortium (YCC) is a recognized authority that provides standardized phylogenetic trees for human Y-chromosome haplogroups, including Haplogroup Q-M242.
What is the primary defining mutation for Haplogroup Q-M242?
Answer: M242 SNP
Explanation: The primary defining mutation for Haplogroup Q-M242 is the M242 single-nucleotide polymorphism (SNP). While M346 is an ancestral SNP to Q-M242, and SNPs like MEH2 and P36.2 have been associated with related haplogroups, M242 is the specific marker that defines this haplogroup.
What are the two main subclades of Haplogroup Q-M242 mentioned in the text?
Answer: Q1/Q-L472 and Q2/Q-L275
Explanation: The two primary subclades of Haplogroup Q-M242 are Q1 (which includes Q-L472 and Q-MEH2) and Q2 (which includes Q-L275).
Which of the following is NOT listed as a specific SNP defining or related to Haplogroup Q-M242 in the source?
Answer: R1b
Explanation: M242 is the defining SNP for Haplogroup Q-M242. L472 is a subclade (Q1/Q-L472), and M346 is an ancestral SNP. R1b is a distinct major haplogroup and is not directly associated with defining Q-M242.
Which of the following is NOT listed as a source for Haplogroup Q-M242 phylogenetic trees?
Answer: National Institutes of Health (NIH)
Explanation: The primary sources for Haplogroup Q-M242 phylogenetic trees mentioned are the Y Chromosome Consortium (YCC), the International Society of Genetic Genealogy (ISOGG), and the Genomic Research Center (GRC) draft tree. The National Institutes of Health (NIH) is not listed as a direct source for these specific trees.
What is the relationship between Haplogroup Q-M242 and Haplogroup R-M207?
Answer: Q-M242 and R-M207 are the two major subclades of Haplogroup P1.
Explanation: Haplogroup Q-M242 and Haplogroup R-M207 are the two principal and most populous subclades that diverged from the ancestral Haplogroup P1.
The estimated origin time for Haplogroup Q-M242 is between 17,000 and 31,700 years ago.
Answer: True
Explanation: Genetic studies estimate the origin of Haplogroup Q-M242 to be within the range of 17,000 to 31,700 years ago, with a commonly cited approximation around 24,500 years before present.
Haplogroup Q-M242 is believed to have originated in the vicinity of the Altai Mountains or South Central Siberia.
Answer: True
Explanation: Genetic evidence suggests that Haplogroup Q-M242 likely originated in the geographical region encompassing the Altai Mountains and South Central Siberia.
Haplogroup Q-M242 is estimated to have originated approximately 10,000 years ago.
Answer: False
Explanation: The estimated origin time for Haplogroup Q-M242 is significantly older, placed between 17,000 and 31,700 years ago, not approximately 10,000 years ago.
According to the source, when did Haplogroup Q-M242 likely originate?
Answer: Approximately 17,000 - 31,700 years ago
Explanation: The estimated origin time for Haplogroup Q-M242 is between 17,000 and 31,700 years ago, with a commonly cited approximation around 24,500 years before present.
Which of the following is a potential origin location for Haplogroup Q-M242?
Answer: The Altai Mountains region
Explanation: The Altai Mountains region, also referred to as South Central Siberia, is considered a likely area of origin for Haplogroup Q-M242.
The Q-M3 subclade is a significant lineage found predominantly among indigenous peoples of the Americas.
Answer: True
Explanation: The Q-M3 subclade, a descendant of Q1a3*-M346, is indeed a predominant Y-DNA lineage among indigenous populations of the Americas, reflecting its importance in the peopling of the continent.
The Saqqaq individual from Greenland belonged to Haplogroup R1a.
Answer: False
Explanation: The Saqqaq individual, an ancient individual from Greenland dating back approximately 4,000 years, belonged to Haplogroup Q1a-MEH2*, not R1a.
Kennewick Man, an ancient North American individual, belonged to Haplogroup Q-M3.
Answer: True
Explanation: Genetic analysis of Kennewick Man, an ancient individual from North America dating back approximately 8,500 years, revealed he belonged to Haplogroup Q1a2-M3.
The Anzick-1 individual, associated with the Clovis culture, belonged to Haplogroup Q-M242.
Answer: True
Explanation: The Anzick-1 individual, an ancient sample associated with the Clovis culture and dating to approximately 12,600 years ago, was found to belong to Haplogroup Q1a2-L54*, a subclade of Q-M242.
Q-P89.1 and Q-NWT01 are identified as potential later arrivals in North America, possibly traveling by boat.
Answer: True
Explanation: The lineages Q-P89.1 and Q-NWT01, found in North American indigenous populations, may represent later migrations that potentially utilized coastal sea routes, distinct from the initial Bering Strait crossing.
Which ancient individual found in Greenland belonged to Haplogroup Q1a-MEH2*?
Answer: The Saqqaq individual
Explanation: The Saqqaq individual, an ancient Paleo-Eskimo from Greenland, belonged to Haplogroup Q1a-MEH2*.
What was the approximate frequency of Haplogroup Q-M242 among Native Americans in the US in 2010?
Answer: 58.1%
Explanation: In 2010, Haplogroup Q-M242 was found in approximately 58.1% of Native Americans in the US. The highest specific frequency reported for a Native American group was 92.3% among the Navajo.
What is the significance of the Q-M3 subclade in the context of the Americas?
Answer: It is the predominant lineage among indigenous peoples of the Americas before European colonization.
Explanation: The Q-M3 subclade is a key lineage within Haplogroup Q-M242 and was the predominant Y-DNA haplogroup among indigenous peoples of the Americas prior to European colonization, indicating its importance in the peopling of the continent.
Which ancient individual, associated with the Clovis culture, belonged to a Q-M242 subclade?
Answer: Anzick-1
Explanation: The Anzick-1 individual, associated with the Clovis culture and dating to approximately 12,600 years ago, belonged to Haplogroup Q1a2-L54*, a subclade of Q-M242.
What is the approximate frequency of Haplogroup Q-M242 among the indigenous peoples of Mesoamerica and South America combined?
Answer: Around 94%
Explanation: Haplogroup Q-M242 is found in approximately 94% of the indigenous populations across Mesoamerica and South America, indicating its widespread prevalence in these regions.
The Q-P89.1 and Q-NWT01 lineages found in North America might represent:
Answer: Populations arriving via later sea voyages along the coast.
Explanation: The Q-P89.1 and Q-NWT01 lineages found among North American indigenous peoples are hypothesized to represent later arrivals, potentially migrating by sea along the coast, rather than being part of the initial Bering Strait migration.
Which specific subclade is predominantly found among indigenous peoples of the Americas and is a descendant of Q1a3*-M346?
Answer: Q-M3
Explanation: The Q-M3 subclade, a descendant of Q1a3*-M346, is predominantly found among indigenous peoples of the Americas and is a key lineage in their genetic history.
Haplogroup Q-M242 is extremely rare in Central Asia.
Answer: False
Explanation: Haplogroup Q-M242 is found at significant frequencies in several Central Asian and Siberian populations, notably among the Ket and Selkup peoples, and various Turkic groups.
Haplogroup Q-M120 is primarily associated with indigenous populations of South America.
Answer: False
Explanation: Haplogroup Q-M120 is primarily found in East Asia, particularly in northern China, and is unique to this region, not associated with South America.
The Ket language, spoken by a population with high Q-M242 frequency, is the only surviving member of the Yeniseian language family.
Answer: True
Explanation: The Ket language is indeed the sole surviving member of the Yeniseian language family, and the Ket people exhibit one of the highest frequencies of Haplogroup Q-M242 globally.
Haplogroup Q-M242 shows a higher frequency in southern China compared to northern China.
Answer: False
Explanation: Haplogroup Q-M242 frequencies are generally higher in northern China, averaging around 4.5%, compared to southern China where frequencies are approximately 2%.
The discovery of Q-M3 samples at a Xiongnu site in Xinjiang suggests a potential link between the Xiongnu and populations speaking Indo-European languages.
Answer: False
Explanation: The presence of Q-M3 samples at a Xiongnu site in Xinjiang suggests a potential connection between the Xiongnu and populations speaking Yeniseian languages, not Indo-European languages. Q-M3 is strongly associated with Native American and Yeniseian groups.
The Swati tribe is mentioned as one of the groups where Haplogroup Q-M242 is predominant.
Answer: True
Explanation: The Swati tribe is cited as one of the populations where Haplogroup Q-M242 constitutes a predominant Y-DNA haplogroup.
The highest frequencies of Haplogroup Q-M242 in Eurasia are found among the Selkup people of Siberia.
Answer: False
Explanation: While the Selkup people exhibit high frequencies (around 66.4%), the Ket people of Siberia show even higher frequencies of Haplogroup Q-M242, reaching up to 93.8%.
Haplogroup Q-M120 is primarily associated with which geographic region?
Answer: East Asia (Northern China)
Explanation: Haplogroup Q-M120 is unique to East Asia and is found most intensively across northern China. It has also been identified in ancient Han Chinese ancestral remains.
Which of the following statements about the Ket people is accurate according to the source?
Answer: They exhibit one of the highest frequencies of Haplogroup Q-M242 globally (93.8%).
Explanation: The Ket people, who speak the sole surviving Yeniseian language, exhibit one of the highest frequencies of Haplogroup Q-M242 globally, reaching 93.8% in some studies.
The presence of Q-M3 samples at a Xiongnu site in Xinjiang suggests a possible connection between the Xiongnu and which language group?
Answer: Yeniseian
Explanation: The discovery of Q-M3 samples at a Xiongnu site in Xinjiang suggests a potential connection between the Xiongnu and speakers of Yeniseian languages, as Q-M3 is strongly associated with Yeniseian and Native American populations.
Which region shows exceptionally high frequencies of Haplogroup Q-M242, second only to the Ket people?
Answer: Northern Siberia (Selkup people)
Explanation: The Selkup people of Northern Siberia exhibit exceptionally high frequencies of Haplogroup Q-M242 (around 66.4%), second only to the Ket people (around 93.8%).
Haplogroup Q-M242 is the predominant Y-DNA haplogroup among indigenous peoples of Australia.
Answer: False
Explanation: Haplogroup Q-M242 is predominantly found among indigenous peoples of the Americas and certain Eurasian populations, not among indigenous Australians.
In 2010, Haplogroup Q-M242 represented approximately 3.1% of the total US population.
Answer: True
Explanation: Estimates from 2010 indicated that Haplogroup Q-M242 comprised approximately 3.1% of the total male population in the United States.
Haplogroup Q-M242 frequencies are generally higher in Southern Europe than in Northern Europe.
Answer: False
Explanation: Haplogroup Q-M242 frequencies generally decrease as one moves westward across Europe. While some specific Southern European locations show higher localized frequencies, Northern Europe generally exhibits higher overall prevalence compared to Southern Europe.
Haplogroup Q-M242 is commonly found in populations across Africa.
Answer: False
Explanation: Haplogroup Q-M242 is rarely found in Africa, with only very low frequencies observed in North Africa and a few other scattered locations.
Haplogroup Q-M242 is estimated to be present in about 0.5% of males worldwide.
Answer: False
Explanation: The estimated global frequency of Haplogroup Q-M242 is approximately 3.1% of males worldwide, not 0.5%.
The Q-M378 subclade is specifically absent in Jewish populations.
Answer: False
Explanation: The Q-M378 subclade has been identified in some European Jewish populations, with its subbranches Q-Y2200 and Q-YP1035 specifically noted within Ashkenazi Jews.
Haplogroup Q-M242 is found at very low frequencies, around 0.5%, in most Western European countries.
Answer: True
Explanation: In most Western European countries, Haplogroup Q-M242 is observed at very low frequencies, typically around 0.5%, although certain localized areas may show higher percentages.
Haplogroup Q-M242 frequencies in the US were highest among the Black population in 2010.
Answer: False
Explanation: In the US in 2010, Haplogroup Q frequencies were highest among Native Americans (58.1%), followed by Latinos (11.7%), and then Whites (0.7%). The Black population showed a frequency of 0.2%.
Haplogroup Q-M242 is found at frequencies around 1.7% in Western Europe.
Answer: False
Explanation: Haplogroup Q-M242 frequencies are typically around 0.5% in most Western European countries. The 1.7% figure is more representative of Central and Eastern Europe.
Which of the following populations is NOT mentioned as having Haplogroup Q-M242 as a predominant Y-DNA haplogroup?
Answer: Indigenous Australians
Explanation: Haplogroup Q-M242 is predominant among Native Americans, various populations in Central Asia, and Northern Siberia. It is not considered predominant among indigenous Australians.
How does the frequency of Haplogroup Q-M242 generally change as one moves westward across Europe?
Answer: It decreases.
Explanation: The frequency of Haplogroup Q-M242 generally decreases as one moves westward across Europe, indicating a higher prevalence in Eastern and Northern European regions compared to Western Europe.
What is the estimated global frequency of Haplogroup Q-M242 among males?
Answer: Approximately 3.1%
Explanation: Based on available data, Haplogroup Q-M242 is estimated to be present in approximately 3.1% of the global male population.
In the US in 2010, which ethnic group showed the highest frequency of Haplogroup Q, excluding Native Americans?
Answer: Latino
Explanation: Excluding Native Americans, the Latino population in the US showed the highest frequency of Haplogroup Q in 2010, at approximately 11.7%.
The Q-M378 subclade is specifically mentioned as being common in which diaspora population?
Answer: European Jewish populations
Explanation: The Q-M378 subclade is noted for being common in certain European Jewish populations, with specific subbranches identified within Ashkenazi Jews.
What is the approximate frequency of Haplogroup Q-M242 in Northern Europe, according to the source?
Answer: 2.5%
Explanation: The frequency of Haplogroup Q-M242 in Northern Europe is approximately 2.5%, with specific examples like 4.1% in Sweden and 2.6% in Norway.
The source mentions specific locations in Southern Europe with notably higher percentages of Haplogroup Q-M242. Which pair is mentioned?
Answer: Hvar Island (Croatia) and Mazara del Vallo (Sicily, Italy)
Explanation: Specific locations in Southern Europe with notably higher percentages of Haplogroup Q-M242 include Hvar Island in Croatia (14.3%) and Mazara del Vallo in Sicily, Italy (16.7%).