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House mouse Wiki2Web Clarity Challenge

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Study Guide: The House Mouse: Biology, Behavior, and Global Impact

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The House Mouse: Biology, Behavior, and Global Impact Study Guide

Taxonomy, Phylogeny, and Evolutionary History

The conservation status of *Mus musculus* as designated by the IUCN Red List is 'Least Concern', not 'Endangered'.

Answer: True

Explanation: The house mouse (*Mus musculus*) is classified as 'Least Concern' on the IUCN Red List, reflecting its widespread distribution and abundant populations.

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The house mouse (*Mus musculus*) is classified within the order Rodentia, not Carnivora.

Answer: True

Explanation: The house mouse belongs to the order Rodentia, characterized by continuously growing incisors, and is not classified under the order Carnivora.

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Mice, belonging to the order Rodentia, are considered among the closest mammalian relatives to primates and lagomorphs.

Answer: True

Explanation: Within the mammalian evolutionary tree, rodents (like mice) and lagomorphs form the clade Glires, and are considered relatively close relatives to primates.

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The subspecies *M. m. domesticus* is predominantly distributed across Europe, North and South America, Africa, and Oceania, not primarily in Asia.

Answer: True

Explanation: The subspecies *M. m. domesticus* has a cosmopolitan distribution, being prevalent across Europe, the Americas, Africa, and Oceania, while *M. m. castaneus* is found in Asia.

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Hybridization between certain house mouse subspecies, such as *M. m. domesticus* and *M. m. musculus* in Europe, typically results in male offspring that are sterile.

Answer: True

Explanation: Hybridization between specific subspecies of house mice, notably in Europe, leads to reproductive isolation mechanisms, including the sterility of male hybrids.

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The standard karyotype of a house mouse (*Mus musculus*) comprises 40 chromosomes, although variations exist.

Answer: True

Explanation: The typical karyotype of the house mouse consists of 40 chromosomes. Certain populations exhibit chromosomal rearrangements, such as Robertsonian fusions, leading to reduced chromosome numbers.

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Genetic research suggests that the origin of the *Mus musculus* species is Southwestern Asia, not North America.

Answer: True

Explanation: Phylogenetic studies indicate that *Mus musculus* originated in Southwestern Asia, with distinct subspecies diverging from ancestral populations in that region.

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What is the conservation status of *Mus musculus* according to the IUCN?

Answer: Least Concern

Explanation: The International Union for Conservation of Nature (IUCN) classifies *Mus musculus* as 'Least Concern' due to its widespread distribution and large population size.

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Which of the following is NOT part of the house mouse's scientific classification?

Answer: Genus Rattus

Explanation: The house mouse belongs to the genus *Mus*. The genus *Rattus* encompasses true rats and is distinct from the classification of *Mus musculus*.

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Which group is considered among the closest mammalian relatives to the house mouse?

Answer: Primates (monkeys and humans)

Explanation: Rodents, including mice, share a relatively close evolutionary relationship with primates and lagomorphs within the mammalian phylogeny.

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Which house mouse subspecies is predominantly found across Europe, North and South America, Africa, and Oceania?

Answer: *M. m. domesticus*

Explanation: The subspecies *M. m. domesticus* exhibits a cosmopolitan distribution, having spread extensively throughout these continents due to human association.

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What is the primary consequence of hybridization between *M. m. domesticus* and *M. m. musculus* in Europe?

Answer: Sterility in male hybrid offspring

Explanation: Hybridization between these subspecies often results in male offspring that are sterile, acting as a post-zygotic barrier that maintains subspecies integrity.

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What is the standard number of chromosomes in a house mouse karyotype?

Answer: 40

Explanation: The diploid chromosome number for the standard house mouse karyotype is 40.

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According to research, where is the likely origin of the *Mus musculus* species?

Answer: Southwestern Asia

Explanation: Genetic and biogeographical evidence points to Southwestern Asia as the region of origin for the *Mus musculus* species complex.

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Morphology, Physiology, and Sensory Perception

The tail of the house mouse is typically short and sparsely furred, serving primarily for balance and thermoregulation, not camouflage.

Answer: True

Explanation: The tail of the house mouse is characterized by being nearly hairless and serves critical functions in balance and thermoregulation, rather than camouflage.

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The house mouse's tail is primarily utilized for balance and thermoregulation, not for defense against predators.

Answer: True

Explanation: The tail of the house mouse is primarily adapted for balance during locomotion and for dissipating excess body heat, not for defensive purposes against predators.

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House mice are omnivorous, consuming plant matter but also other available food sources, and exhibit coprophagia.

Answer: True

Explanation: House mice possess an omnivorous diet and exhibit coprophagia (consumption of feces) as a means to reabsorb nutrients produced by gut flora.

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House mice, like other rodents, are physiologically incapable of vomiting.

Answer: True

Explanation: The anatomy of the rodent gastrointestinal tract prevents house mice from vomiting, a trait that influences their vulnerability to ingested toxins.

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House mice possess dichromatic color vision, which is more limited than human trichromatic vision.

Answer: True

Explanation: Compared to humans (trichromats), house mice have dichromatic color vision, indicating a reduced capacity for color discrimination.

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Aging in house mice is characterized by increased DNA damage and heightened sensitivity to oxidative stress.

Answer: True

Explanation: Cellular senescence in aging mice is associated with elevated levels of DNA damage markers and an increased susceptibility to oxidative damage.

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The vomeronasal organ in house mice is primarily responsible for detecting pheromones, not sounds.

Answer: True

Explanation: The vomeronasal organ is a specialized sensory structure dedicated to the detection of pheromonal cues, which are critical for social and reproductive behaviors in mice.

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House mouse whiskers (vibrissae) are primarily sensory organs used for tactile navigation and sensing air movements, not grooming.

Answer: True

Explanation: Vibrissae are highly sensitive tactile hairs that enable house mice to perceive their environment, particularly in low-light conditions, by sensing surfaces and air currents.

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Dietary restriction in mice has been shown to reduce DNA damage, potentially retarding aging processes.

Answer: True

Explanation: Studies indicate that caloric restriction can mitigate age-related increases in DNA damage, suggesting a mechanism by which it retards the aging process.

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The house mouse's tail plays a crucial role in thermoregulation by dissipating excess body heat, in addition to aiding balance.

Answer: True

Explanation: The tail's extensive vascularization allows for significant heat exchange, making it a vital organ for thermoregulation in house mice.

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A thick, furry tail is NOT typical of a wild house mouse; their tails are generally long and sparsely furred.

Answer: A thick, furry tail

Explanation: Wild house mice are characterized by a long, sparsely furred tail, which contrasts with a thick, furry tail that is not a typical feature.

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What is the primary function of the house mouse's tail in thermoregulation?

Answer: Dissipating excess body heat through its skin

Explanation: The tail's extensive vascular network facilitates the dissipation of excess body heat, playing a critical role in maintaining thermal homeostasis.

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What unique feeding behavior is characteristic of house mice?

Answer: Eating their own feces (coprophagia)

Explanation: Coprophagia, the consumption of fecal pellets, is a characteristic feeding behavior in house mice, enabling the re-ingestion and absorption of nutrients synthesized by gut microbiota.

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How does house mouse color vision differ from human vision?

Answer: Mice are dichromats, with more limited color perception than humans.

Explanation: House mice possess dichromatic color vision, meaning they utilize two types of cone photoreceptors, resulting in a less nuanced perception of color compared to human trichromacy.

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How does dietary restriction affect aging in house mice, according to cellular studies?

Answer: It reduces DNA damage (8-oxo-dG levels).

Explanation: Cellular studies indicate that dietary restriction in mice is associated with a reduction in age-related DNA damage, such as 8-oxo-dG levels, suggesting a role in retarding aging.

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What is the primary role of the vomeronasal organ in house mice?

Answer: Detecting pheromones

Explanation: The vomeronasal organ is specialized for the detection of pheromones, which are crucial chemical signals mediating social and reproductive behaviors in house mice.

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What sensory function do whiskers (vibrissae) primarily serve for house mice?

Answer: Sensing surfaces and air movements for navigation

Explanation: Whiskers are highly sensitive tactile sensors that house mice use extensively for spatial orientation, navigation, and exploring their immediate environment, particularly in darkness.

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How does dietary restriction impact the aging process in house mice?

Answer: It significantly slows aging by reducing DNA damage.

Explanation: Dietary restriction has been shown to decelerate aging in house mice, primarily by mitigating the accumulation of DNA damage and reducing oxidative stress.

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What is the significance of the house mouse's inability to vomit?

Answer: It makes them more vulnerable to ingested poisons.

Explanation: The physiological inability to vomit means that house mice cannot easily expel ingested toxins, rendering them more susceptible to poisoning compared to species capable of emesis.

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Behavioral Ecology and Social Dynamics

House mice are primarily crepuscular or nocturnal, exhibiting peak activity during twilight hours or at night, not during daylight.

Answer: True

Explanation: House mice generally exhibit crepuscular or nocturnal activity patterns, avoiding bright daylight conditions and preferring to forage and move during twilight or nighttime.

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House mice are social animals and do not typically live solitarily; they often form complex social structures.

Answer: True

Explanation: Contrary to being solitary, house mice often live in social groups, exhibiting territoriality and complex interactions, particularly in commensal environments.

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Commensal house mouse populations, benefiting from abundant food resources, tend to exhibit lower levels of female-female aggression compared to noncommensal populations.

Answer: True

Explanation: Resource availability influences social dynamics; in commensal settings with ample food, female-female aggression is reduced, whereas in resource-scarce noncommensal environments, it is more pronounced.

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Pheromones play a significant role in house mouse communication, influencing various social and reproductive behaviors.

Answer: True

Explanation: Chemical communication via pheromones is fundamental to house mouse social structure, mediating behaviors from reproduction synchronization to territorial marking.

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Male house mice court females using ultrasonic calls, typically in the 30-110 kHz range, which are inaudible to humans.

Answer: True

Explanation: Courtship vocalizations in male house mice occur predominantly in the ultrasonic spectrum, beyond human hearing capabilities.

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Domestication can rapidly alter mouse behavior. Captive-reared mice can differ significantly in boldness and activity patterns from their wild-caught counterparts within just four to five generations.

Answer: True

Explanation: Selective pressures in captivity can induce rapid behavioral changes in house mice, demonstrating the plasticity of their behavioral repertoire across generations.

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The 'Bruce effect' in house mice refers to the termination of pregnancy in females exposed to the scent of an unfamiliar male, not the synchronization of estrus cycles.

Answer: True

Explanation: The Bruce effect describes the phenomenon where pregnancy is terminated upon exposure to the pheromones of a novel male, distinct from the Whitten effect which synchronizes estrus cycles.

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Tripoding is a behavior observed in house mice where they use their tail for support while standing erect on their hind legs.

Answer: True

Explanation: Tripoding, a posture involving the use of the tail as a third point of support, is employed by house mice for enhanced stability during feeding, vigilance, or combat.

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House mice are most active during which times?

Answer: Both B and C

Explanation: House mice typically exhibit crepuscular and nocturnal activity patterns, being most active during twilight hours and throughout the night.

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How do male house mice typically establish and defend their territories?

Answer: Using urine scent marks

Explanation: Urine scent marking is a primary method by which male house mice delineate and defend their territories from conspecific intruders.

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Which social behavior is more pronounced in noncommensal house mouse populations compared to commensal ones?

Answer: Higher female-female aggression

Explanation: In noncommensal populations, where resources are often limited, increased competition leads to more pronounced female-female aggression compared to the dynamics observed in resource-rich commensal settings.

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The 'Whitten effect' in house mice refers to:

Answer: The synchronization of estrus cycles in females exposed to male odor.

Explanation: The Whitten effect describes the phenomenon where exposure to male pheromones synchronizes the estrous cycles of female mice, facilitating group pregnancy.

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Male house mice communicate courtship through:

Answer: Complex ultrasonic calls

Explanation: Male house mice employ complex ultrasonic vocalizations during courtship, which are integral to their mating behavior and communication with females.

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What behavioral difference is noted between captive-reared and wild-caught house mice after several generations?

Answer: Captive mice are significantly bolder.

Explanation: Domestication processes can lead to rapid changes in behavior, with captive-reared house mice often displaying increased boldness compared to their wild counterparts within a few generations.

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Reproductive Biology and Life Cycle

The estrous cycle of a female house mouse is typically much shorter, lasting approximately four to six days.

Answer: True

Explanation: Female house mice exhibit a short estrous cycle, typically recurring every four to six days, which facilitates their high reproductive potential.

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The gestation period for house mice is typically around 19 to 21 days, not over 30 days.

Answer: True

Explanation: The typical gestation period for *Mus musculus* is approximately 19 to 21 days, allowing for rapid population turnover.

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House mouse pups are born altricial, meaning they are born without fur and with their eyes closed.

Answer: True

Explanation: Newborn house mouse pups are altricial, lacking fur and possessing undeveloped sensory organs, requiring significant parental care for survival.

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Polygamy, particularly mate-defense polygyny, is the most common mating system observed in house mice.

Answer: True

Explanation: The predominant mating system in house mice is polygamous, often characterized by males defending territories that encompass multiple females.

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Polyandry in house mice generally increases genetic diversity within litters, rather than decreasing it.

Answer: True

Explanation: Polyandrous mating strategies in house mice contribute to increased genetic diversity within litters, which can confer evolutionary advantages.

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House mice possess several mechanisms to avoid inbreeding, including kin recognition via pheromones and potential sperm selection favoring unrelated males.

Answer: True

Explanation: Mechanisms such as olfactory recognition of kin via Major Urinary Proteins (MUPs) and potential cryptic female choice in sperm selection help house mice mitigate the risks of inbreeding.

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Male and female house mice are distinguishable at birth. While specific physical characteristics at birth are not detailed in the provided data, their distinct reproductive roles and cycles, such as males defending territories and females exhibiting estrous cycles, indicate inherent differences.

Answer: False

Explanation: The statement that male and female house mice are indistinguishable at birth is false. While specific physical markers at birth are not detailed, their distinct reproductive physiology and social roles imply distinguishability.

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The Major Urinary Protein (MUP) gene cluster plays a role in mate selection, particularly in kin recognition and avoidance of inbreeding.

Answer: True

Explanation: The polymorphic MUPs in house mouse urine serve as olfactory signals that facilitate the recognition of kin and influence mate choice, thereby promoting outbreeding.

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What is the typical duration of a house mouse's estrous cycle?

Answer: 4 to 6 days

Explanation: The estrous cycle in female house mice typically spans approximately four to six days, allowing for frequent reproductive opportunities.

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What is the average litter size for house mice?

Answer: 6-8 pups

Explanation: The average litter size for house mice typically ranges from six to eight pups, contributing to their rapid population growth potential.

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At approximately what age are house mouse pups typically weaned?

Answer: 21 days

Explanation: House mouse pups are typically weaned around 21 days of age, coinciding with the development of their ability to consume solid food.

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Which mating system is most common in house mice, involving males defending territories with multiple females?

Answer: Mate-defense polygyny

Explanation: Mate-defense polygyny, where males monopolize access to multiple females by defending their territories, is the most prevalent mating system observed in house mice.

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What is a significant benefit of polyandry in house mice?

Answer: Increased genetic diversity within litters

Explanation: Polyandry enhances reproductive success by increasing the genetic diversity of offspring within a litter, which can improve their survival rates and adaptive potential.

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Global Distribution and Ecological Impact

Outside of human settlements, house mice are generally poor competitors and often cannot survive if species like wood mice are present.

Answer: True

Explanation: In natural environments, house mice often exhibit competitive inferiority compared to native small mammals such as wood mice, limiting their survival outside of human-associated habitats.

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Wild house mice typically have a lifespan of less than one year due to high predation rates, not several years.

Answer: True

Explanation: The precarious existence of wild house mice, marked by significant predation pressure, results in a typical lifespan considerably shorter than one year.

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The global spread of house mice has been primarily facilitated by human activities, such as trade and transportation, rather than natural migration independent of humans.

Answer: True

Explanation: Human expansion and global trade routes have been the principal vectors for the dispersal of *Mus musculus* across continents, rather than independent natural migration.

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On islands, house mice are frequently considered invasive species due to their significant ecological impact.

Answer: True

Explanation: Introduced house mice often exhibit invasive behavior on islands, disrupting native ecosystems through competition and predation.

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The house mouse's remarkable adaptability is a major factor contributing to its widespread success and colonization of diverse habitats.

Answer: True

Explanation: The capacity of *Mus musculus* to thrive in a wide array of environmental conditions, including those modified by human activity, is central to its status as a globally successful species.

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On islands, house mice often negatively impact native ecosystems by competing with native wildlife for food and preying on smaller native animals, rather than benefiting them.

Answer: True

Explanation: As invasive species on islands, house mice can exert considerable pressure on native fauna and flora through competition for resources and direct predation.

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In competition with other small mammals outside human settlements, house mice often:

Answer: Cannot survive if species like wood mice are present.

Explanation: Outside of human-associated environments, house mice frequently exhibit competitive disadvantages against native rodent species, limiting their establishment.

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What is the typical lifespan of a house mouse in the wild?

Answer: Less than 1 year

Explanation: Due to high predation and environmental challenges, the typical lifespan of a house mouse in its natural wild habitat is less than one year.

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How did house mice historically spread to the Americas?

Answer: Via Spanish ships in the early 16th century

Explanation: The introduction of house mice to the Americas is largely attributed to their transport aboard European vessels, particularly Spanish ships, during the early period of exploration and colonization.

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What impact have house mice had as invasive species on islands like Gough Island?

Answer: They have become unusually large and prey on seabird chicks.

Explanation: On islands such as Gough Island, invasive house mice have exhibited gigantism and prey upon native seabird chicks, causing significant ecological disruption.

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Which statement best describes the role of house mice in island ecosystems where they are invasive?

Answer: They compete with native wildlife for food and can prey on smaller native animals.

Explanation: In island ecosystems, invasive house mice often disrupt native food webs by competing for resources and preying upon vulnerable indigenous species.

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Human-Mouse Interactions: Pests, Models, and Culture

House mice are believed to have facilitated, rather than deterred, the domestication of cats by providing a consistent food source in human settlements.

Answer: True

Explanation: The presence of abundant house mice in early human settlements likely attracted wild cats, establishing a commensal relationship that contributed significantly to feline domestication.

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The practice of keeping mice as pets dates back much earlier than the 20th century, with historical references found as early as 1100 BC.

Answer: True

Explanation: Historical records indicate that mice have been kept as pets or for other purposes for millennia, predating the 20th century by a considerable margin.

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House mice are generally considered pests in agricultural settings, not beneficial animals, due to their consumption of crops and contamination of stored grains.

Answer: True

Explanation: In agricultural contexts, house mice are primarily viewed as pests due to their detrimental impact on crops and stored food resources.

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While house mice can carry diseases, they are not considered primary vectors for transmitting the human plague; other rodents and their fleas are more directly implicated.

Answer: True

Explanation: Although capable of harboring pathogens, house mice are not typically the primary vectors for the transmission of the human plague, unlike certain other rodent species and their associated fleas.

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House mice play a role in the Lyme disease cycle by serving as hosts for immature ticks that acquire the bacteria, thus indirectly contributing to disease transmission.

Answer: True

Explanation: By serving as a reservoir for the bacteria causing Lyme disease in immature ticks, house mice are integral to the ecological transmission cycle of this illness.

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Mice are valuable models for human genetic research due to significant genetic homology, not divergence, with humans.

Answer: True

Explanation: The extensive genetic similarity between mice and humans underpins their utility as model organisms for studying human biology and disease.

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In folklore, house mice are often depicted as pests or tricksters, rather than primarily as symbols of good fortune.

Answer: True

Explanation: While specific cultural interpretations vary, house mice frequently appear in folklore as common pests or characters embodying cunning, rather than solely as symbols of prosperity.

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The abundance of house mice in human settlements is considered a key factor that attracted wild cats, thereby aiding their domestication.

Answer: True

Explanation: The consistent availability of house mice as a food source in proximity to human dwellings is hypothesized to have been a primary driver for the initial attraction and subsequent domestication of cats.

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House mouse infestations pose significant health risks to humans, including the transmission of diseases and contamination of food supplies.

Answer: True

Explanation: Infestations by house mice present considerable public health concerns due to their potential to transmit pathogens and contaminate food and surfaces with excreta.

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The 'fancy mouse' refers to domesticated varieties of the house mouse bred for specific traits, not a wild subspecies found in Europe.

Answer: True

Explanation: 'Fancy mice' are selectively bred domestic strains, differing morphologically and behaviorally from their wild counterparts, and are not a distinct wild subspecies.

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Mice are valuable models for human genetic research due to significant genetic homology, not divergence, with humans.

Answer: True

Explanation: The substantial genetic similarity between mice and humans is the primary reason for their extensive use in biomedical research, enabling the study of conserved biological processes.

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In South Slavic folklore, 'Mouse Day' is often associated with spring festivals in the western Balkans and harvest celebrations in the eastern Balkans.

Answer: True

Explanation: Traditional observances of 'Mouse Day' among South Slavic cultures exhibit regional variations, often linked to seasonal agricultural cycles and festivals.

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What role did house mice play in the domestication of cats?

Answer: Their presence attracted wild cats to human settlements.

Explanation: The abundance of house mice in human habitations provided a readily available food source that drew wild cats, initiating a commensal relationship that facilitated their domestication.

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Which of the following is a significant way house mice act as pests in human environments?

Answer: Contaminating food supplies

Explanation: House mice are considered significant pests due to their habit of contaminating stored food and agricultural products with their excreta and urine.

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Which disease can house mice transmit, particularly posing a risk to pregnant women?

Answer: Lymphocytic choriomeningitis (LCMV)

Explanation: Lymphocytic choriomeningitis virus (LCMV) is a pathogen that can be transmitted by house mice and poses a particular risk of severe complications, especially to pregnant women.

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How do house mice contribute to the spread of Lyme disease?

Answer: By acting as hosts for tick larvae that acquire the bacteria.

Explanation: House mice serve as critical hosts for the larval stages of ticks, enabling these immature vectors to become infected with the Lyme disease bacterium, Borrelia burgdorferi.

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Why are mice extensively used as model organisms in scientific research?

Answer: They have significant genetic homology with humans.

Explanation: The high degree of genetic similarity between mice and humans, coupled with their rapid reproduction and ease of manipulation, makes them invaluable models for studying human biology and disease.

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In South Slavic folklore, 'Mouse Day' is often associated with:

Answer: Both A and B, depending on the region.

Explanation: The traditional 'Mouse Day' celebrations among South Slavic peoples are observed in different regions during either spring or autumn, often coinciding with agricultural cycles or religious festivals.

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