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The NEJM was founded in the 19th century by a physician named John Collins Warren.
Answer: True
Explanation: The founding of The New England Journal of Medicine occurred in 1812, which is in the 19th century, by John Collins Warren.
Initially, upon its founding in 1812, the journal was published on a quarterly basis.
Answer: True
Explanation: The journal's initial publication frequency upon its founding in 1812 was quarterly.
The journal adopted its current name, The New England Journal of Medicine, in 1928.
Answer: True
Explanation: The journal was officially renamed The New England Journal of Medicine in 1928.
The Massachusetts Medical Society purchased the journal in 1921 for US$1.
Answer: True
Explanation: The Massachusetts Medical Society acquired the journal in 1921 for US$1, with the journal being renamed The New England Journal of Medicine in 1928.
Who is credited as the founder of The New England Journal of Medicine in 1812?
Answer: John Collins Warren
Explanation: John Collins Warren is credited as the founder of the journal in 1812.
In 1828, the journal merged with the 'Boston Medical Intelligencer', leading to the formation of the 'Boston Medical and Surgical Journal' and a shift to weekly publication.
Answer: True
Explanation: The merger in 1828 involved the 'Boston Medical Intelligencer' and resulted in the 'Boston Medical and Surgical Journal', which adopted a weekly publication schedule.
What does the date '1828' signify in the history of NEJM's predecessors?
Answer: The merger with the Boston Medical Intelligencer and shift to weekly publication.
Explanation: The year 1828 signifies the merger with the 'Boston Medical Intelligencer', leading to the formation of the 'Boston Medical and Surgical Journal' and a shift to weekly publication.
What historical event does the date '1928' represent in the NEJM's history?
Answer: The official renaming of the journal to The New England Journal of Medicine.
Explanation: The year 1928 signifies the official renaming of the journal to 'The New England Journal of Medicine'.
The New England Journal of Medicine (NEJM) is published weekly by the Massachusetts Medical Society.
Answer: True
Explanation: The source material indicates that NEJM is published weekly by the Massachusetts Medical Society.
Eric Rubin is the current editor-in-chief of The New England Journal of Medicine.
Answer: True
Explanation: Eric Rubin holds the position of current editor-in-chief for The New England Journal of Medicine.
The Massachusetts Medical Society is the publisher of The New England Journal of Medicine.
Answer: True
Explanation: The Massachusetts Medical Society serves as the publisher for The New England Journal of Medicine.
NEJM articles become open access immediately upon publication.
Answer: False
Explanation: NEJM articles are typically made available through delayed open access six months after publication, although articles of global public health importance may be immediately accessible.
Authors are charged significant fees for submitting and publishing articles in NEJM.
Answer: False
Explanation: The New England Journal of Medicine does not charge authors any submission or publication fees.
The Ingelfinger rule requires that submitted articles must not have been previously published or released elsewhere.
Answer: True
Explanation: The Ingelfinger rule mandates that articles submitted to NEJM must not have been previously published or released elsewhere, ensuring peer review precedes dissemination.
According to NEJM's open access policy, when are articles typically made freely available?
Answer: Six months after publication
Explanation: NEJM articles are typically made freely available six months after their initial publication date.
The Ingelfinger rule, maintained by NEJM, primarily serves to:
Answer: Ensure all published articles are peer-reviewed before public release.
Explanation: The Ingelfinger rule mandates that research submitted to NEJM must not have been previously published or released elsewhere. Its primary purpose is to ensure that all published research has undergone rigorous peer review before dissemination to the professional community and the public.
What policy does NEJM maintain regarding the prior release of submitted research?
Answer: Articles must not have been previously published or released elsewhere.
Explanation: NEJM maintains a policy that articles submitted for publication must not have been previously published or released elsewhere.
The primary focus of The New England Journal of Medicine is engineering and technology.
Answer: False
Explanation: The primary discipline covered by The New England Journal of Medicine is Medicine, not engineering and technology.
The New England Journal of Medicine is published in multiple languages, including French and Spanish.
Answer: False
Explanation: The New England Journal of Medicine is published exclusively in English.
The NEJM logo features the Rod of Asclepius symbol crossed with a quill pen.
Answer: True
Explanation: The NEJM logo depicts the Rod of Asclepius crossed over a quill pen.
The CODEN identifier for The New England Journal of Medicine is NEJMAG.
Answer: True
Explanation: The CODEN identifier assigned to The New England Journal of Medicine is NEJMAG.
What is the primary role of The New England Journal of Medicine (NEJM)?
Answer: A prestigious, globally recognized weekly peer-reviewed medical journal.
Explanation: The New England Journal of Medicine functions as a prestigious, globally recognized weekly peer-reviewed medical journal.
What is the current publication frequency of The New England Journal of Medicine?
Answer: Weekly
Explanation: The New England Journal of Medicine is currently published on a weekly basis.
What does the NEJM logo symbolize, combining medical and literary elements?
Answer: The Rod of Asclepius crossed over a quill pen
Explanation: The NEJM logo symbolizes the Rod of Asclepius crossed over a quill pen, representing medicine and scholarly writing.
What is the CODEN identifier assigned to The New England Journal of Medicine?
Answer: NEJMAG
Explanation: The CODEN identifier assigned to The New England Journal of Medicine is NEJMAG.
What does the print ISSN for The New England Journal of Medicine indicate?
Answer: A standard number assigned to the print version for identification.
Explanation: The print ISSN (International Standard Serial Number) for The New England Journal of Medicine is 0028-4793, serving as a standard numerical identifier for the print edition.
Henry Jacob Bigelow's 1846 report in NEJM detailed the first successful use of ether as a general anesthetic.
Answer: True
Explanation: In November 1846, the journal published Henry Jacob Bigelow's report on the first public demonstration of inhaled ether as a generalized anesthetic.
James Homer Wright's 1906 article detailed observations of megakaryocytes and platelets.
Answer: True
Explanation: James Homer Wright's 1906 publication in NEJM described observations of megakaryocytes and platelets.
Charles-Édouard Brown-Séquard's 1872 publication proposed that one cerebral hemisphere could influence both sides of the body.
Answer: True
Explanation: Brown-Séquard's 1872 publication suggested that one cerebral hemisphere could influence both sides of the body, and he is also known for describing the Brown-Séquard syndrome.
Sidney Farber reported success in treating childhood leukemia using aminopterin in 1948.
Answer: True
Explanation: In June 1948, Sidney Farber reported promising results in treating acute lymphoblastic leukemia in children using aminopterin.
Paul Zoll's 1952 publication detailed the use of an external electric pacemaker for ventricular standstill.
Answer: True
Explanation: Paul Zoll's 1952 report described the use of an external electric pacemaker to treat ventricular standstill.
A 1973 article in NEJM introduced the concept of polyp removal via colonoscopy for cancer prevention.
Answer: True
Explanation: In February 1973, the journal published the first report on polyp removal using a colonoscope, a procedure that could reduce cancer risk.
Landmark articles describing the disease now known as AIDS were published in NEJM in December 1981.
Answer: True
Explanation: In December 1981, two landmark articles published in NEJM described the clinical course of patients with the disease that would become known as AIDS.
Brian Druker's 2001 NEJM report focused on a new treatment for chronic myelogenous leukemia (CML).
Answer: True
Explanation: Brian Druker's 2001 report detailed a targeted therapy for chronic myelogenous leukemia (CML).
A 2021 study compared psilocybin to an SSRI for treating major depressive disorder, finding no significant difference in effectiveness after six weeks.
Answer: True
Explanation: The 2021 NEJM study comparing psilocybin and escitalopram for major depressive disorder found no significant difference in effectiveness between the two treatments after six weeks.
Which significant medical advancement was reported in NEJM in November 1846?
Answer: The first public demonstration of ether as a general anesthetic
Explanation: The report on the first public demonstration of ether as a general anesthetic was published in NEJM in November 1846.
What discovery related to blood components was detailed by James Homer Wright in 1906?
Answer: The description of megakaryocytes and platelets
Explanation: James Homer Wright's 1906 article detailed observations of megakaryocytes and platelets.
In December 1981, NEJM published landmark articles describing the initial cases of which disease?
Answer: Acquired Immunodeficiency Syndrome (AIDS)
Explanation: In December 1981, NEJM published landmark articles describing the initial cases of what would become known as Acquired Immunodeficiency Syndrome (AIDS).
What type of therapy for chronic myelogenous leukemia (CML) was reported by Brian Druker and colleagues in NEJM in 2001?
Answer: A targeted inhibitor of the BCR-ABL tyrosine kinase
Explanation: The 2001 NEJM report by Brian Druker and colleagues detailed a targeted therapy using an inhibitor of the BCR-ABL tyrosine kinase for chronic myelogenous leukemia (CML).
The 2021 study comparing psilocybin and escitalopram for depression found:
Answer: There was no significant difference in effectiveness between the two treatments after six weeks.
Explanation: The 2021 NEJM study comparing psilocybin and escitalopram for major depressive disorder found no significant difference in effectiveness between the two treatments after six weeks.
NEJM launched its website and began electronic publication in 1996.
Answer: True
Explanation: NEJM launched its website and commenced electronic publication on April 25, 1996.
NEJM Evidence is a monthly publication focused on original research and clinical trials in medicine.
Answer: True
Explanation: NEJM Evidence, launched in 2022, is a monthly digital sub-journal dedicated to publishing original research and clinical trials in medicine.
NEJM launched its website and began electronic publication on which date?
Answer: April 25, 1996
Explanation: NEJM launched its website and commenced electronic publication on April 25, 1996.
Which of the following is NOT a feature developed by NEJM to enhance its digital presence?
Answer: A comprehensive medical coding simulator
Explanation: While NEJM offers features like 'Videos in Clinical Medicine,' 'Interactive Medical Cases,' and the 'NEJM Archive' to enhance its digital presence, a comprehensive medical coding simulator is not among the listed digital features.
What is the primary focus of the NEJM sub-journal 'NEJM Evidence,' launched in 2022?
Answer: Publishing original research and clinical trials in medicine
Explanation: NEJM Evidence is dedicated to publishing original research and clinical trials in medicine.
The 'Videos in Clinical Medicine' feature on the NEJM website is primarily intended to:
Answer: Teach medical procedures and examination techniques
Explanation: The 'Videos in Clinical Medicine' feature is designed to teach skilled techniques and specialized physical examinations required in medical practice.
What was the significance of the 1977 George Polk Award given to NEJM?
Answer: It marked the journal's first major award.
Explanation: The 1977 George Polk Award was significant as it provided The New England Journal of Medicine with its first substantial mainstream visibility, contributing to its subsequent prestige and recognition.