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Ecgonine is primarily recognized for its application as a common anesthetic agent.
Answer: False
The provided source material does not explicitly state that ecgonine is primarily known as an anesthetic agent. While its classification as a Schedule II controlled substance in the United States suggests potential accepted medical uses, the primary focus of the information pertains to its chemical structure, its relationship with cocaine, and its regulatory status.
The chemical nomenclature '3-Hydroxytropane-2-carboxylic acid' is an accepted IUPAC designation for ecgonine.
Answer: True
The systematic IUPAC nomenclature for ecgonine includes '3-Hydroxytropane-2-carboxylic acid' as a valid designation, reflecting its chemical structure.
Ecgonine is classified as a simple amine, lacking any acidic or alcoholic properties.
Answer: False
Ecgonine possesses multiple chemical functionalities, acting as a tertiary base, an acid (specifically a carboxylic acid), and an alcohol, contrary to the assertion of lacking these properties.
The molar mass of ecgonine is approximately 185.223 grams per mole.
Answer: True
The molar mass of ecgonine is accurately stated as 185.223 grams per mole (g/mol).
Ecgonine exhibits structural similarity to tropine, with the sole difference being the presence of a hydroxyl group on ecgonine.
Answer: False
Ecgonine is chemically recognized as the carboxylic acid analog of tropine. This designation indicates that ecgonine possesses a carboxylic acid group, in addition to other functional groups, which represents a more substantial structural difference than solely the presence of a hydroxyl group.
The density of ecgonine is reported as approximately 1.293 g/cm³.
Answer: True
The density of ecgonine is reported in the source material as 1.293 ± 0.06 grams per cubic centimeter (g/cm³).
When ecgonine crystallizes, it forms an anhydrous compound.
Answer: False
The crystallization of ecgonine results in the formation of a hydrated compound, incorporating one molecule of water.
The standard state conditions mentioned for ecgonine properties are 0 degrees Celsius and 1 atm.
Answer: False
The standard state conditions typically referenced for chemical properties are 25 degrees Celsius (298.15 K) and 100 kilopascals (approximately 1 atm), not 0 degrees Celsius.
Ecgonine exhibits dextrorotary optical activity.
Answer: False
Ecgonine exhibits levorotary optical activity, meaning it rotates the plane of polarized light in a counter-clockwise direction.
Ecgonine is chemically described as the primary alcohol analog of tropine.
Answer: False
Ecgonine is chemically described as the carboxylic acid analog of tropine, not the primary alcohol analog.
A ball-and-stick model of ecgonine illustrates its chemical formula.
Answer: False
A ball-and-stick model illustrates the three-dimensional atomic structure and spatial arrangement of atoms within a molecule, rather than simply its chemical formula.
Ecgonine is a tropane alkaloid, primarily defined by the presence of a piperidine ring structure.
Answer: False
While ecgonine is indeed a tropane alkaloid, its defining structural characteristic is a bicyclic amine system, specifically the tropane skeleton, rather than solely a piperidine ring structure. The tropane structure is a bicyclic compound containing a nitrogen bridge.
The melting point of crystallized ecgonine hydrate is between 198-199 degrees Fahrenheit.
Answer: False
The melting point of crystallized ecgonine hydrate is reported in Celsius (198-199 °C), not Fahrenheit. The Fahrenheit equivalent is approximately 388-390 °F.
Identify a correct IUPAC nomenclature for ecgonine as presented in the source material.
Answer: 3-Hydroxytropane-2-carboxylic acid
The source material explicitly lists '3-Hydroxytropane-2-carboxylic acid' as a correct IUPAC name for ecgonine.
What is the precise molar mass of ecgonine, as indicated in the provided data?
Answer: 185.223 g/mol
The source material specifies the molar mass of ecgonine to be 185.223 grams per mole (g/mol).
Regarding the crystallization of ecgonine, what physical characteristic is noted in the source material?
Answer: It incorporates one molecule of water, forming a hydrate.
The source material specifies that when ecgonine crystallizes, it forms a hydrated compound, incorporating one molecule of water per molecule of ecgonine.
Ecgonine is fundamentally classified within which category of chemical compounds?
Answer: A tropane alkaloid
The source material classifies ecgonine as a tropane alkaloid, a group of organic compounds defined by their characteristic bicyclic amine structure.
What is indicated by the source regarding the optical activity of ecgonine?
Answer: It is levorotary.
The provided source material explicitly states that ecgonine exhibits levorotary optical activity.
Which visualization tool is indicated by the source for interacting with ecgonine's molecular structure?
Answer: JSmol
The source material provides access to an interactive 3D model of ecgonine, which can be visualized using tools such as JSmol.
What is the molecular chemical formula for ecgonine?
Answer: C9H15NO3
The chemical formula for ecgonine, indicating the number of atoms of each element in a molecule, is C9H15NO3.
What information is conveyed by the depiction of ecgonine's semi-skeletal formula?
Answer: Its chemical structure in a common format
The semi-skeletal formula provides a common and standardized representation of ecgonine's chemical structure, illustrating the arrangement of atoms and bonds.
Ecgonine is chemically characterized as the carboxylic acid analog of which related compound?
Answer: Tropine
The source material identifies ecgonine as the carboxylic acid analog of tropine, indicating a shared structural foundation with the addition of a carboxylic acid functional group.
What value is reported for the density of ecgonine in the provided documentation?
Answer: 1.293 g/cm³ ± 0.06
The density of ecgonine is reported in the source material as 1.293 ± 0.06 grams per cubic centimeter (g/cm³).
What is the specified melting point range for crystallized ecgonine hydrate?
Answer: 198-199 °C
Crystallized ecgonine hydrate exhibits a melting point range of 198 to 199 degrees Celsius.
According to the provided information, what is the chemical relationship between ecgonine and tropine?
Answer: Ecgonine is the carboxylic acid analog of tropine.
The source material defines the chemical relationship by stating that ecgonine is the carboxylic acid analog of tropine.
Ecgonine is naturally occurring within the root structures of the tobacco plant.
Answer: False
The source material indicates that ecgonine is naturally found in the leaves of the coca plant, not in the roots of the tobacco plant.
Ecgonine is a metabolite of cocaine but cannot be synthesized into cocaine.
Answer: False
The source material indicates that ecgonine functions as both a metabolite of cocaine and a precursor from which cocaine can be synthesized.
Hydrolysis of cocaine can yield ecgonine.
Answer: True
The process of hydrolysis applied to cocaine can indeed result in the formation of ecgonine.
Ecgonine exhibits a significant chemical relationship with cocaine, serving as both a metabolic byproduct of cocaine breakdown and a compound from which cocaine can be synthesized.
Answer: True
The source material confirms that ecgonine is chemically related to cocaine. It functions as a metabolite, meaning it is produced during the body's metabolic processing of cocaine, and also as a precursor, a substance that can be utilized in the synthesis of cocaine.
What is identified as the principal natural source of ecgonine within the provided documentation?
Answer: The leaves of the coca plant
The source material explicitly states that ecgonine is naturally present in the leaves of the coca plant.
Based on the provided information, what is the established relationship between ecgonine and cocaine?
Answer: Ecgonine is a metabolite and a precursor of cocaine.
The source material clearly delineates the relationship: ecgonine functions as both a metabolite, produced during the body's processing of cocaine, and a precursor, a substance from which cocaine can be synthesized.
In the context of ecgonine's relationship with cocaine, what does the term 'metabolite' signify?
Answer: Ecgonine is a substance produced when the body processes cocaine.
The term 'metabolite' signifies that ecgonine is a compound generated through the body's metabolic breakdown of cocaine.
The CAS Registry Number for ecgonine is 481-37-8.
Answer: True
The CAS Registry Number assigned to ecgonine is indeed 481-37-8, serving as a unique numerical identifier.
The SMILES notation for ecgonine is O=C(O)[C@H]1[C@@H](O)C[C@H]2N(C)[C@@H]1CC2.
Answer: True
The provided SMILES notation, O=C(O)[C@H]1[C@@H](O)C[C@H]2N(C)[C@@H]1CC2, accurately represents the chemical structure of ecgonine.
The ChEBI identifier for ecgonine is CHEBI:4743.
Answer: True
The ChEBI (Chemical Entities of Biological Interest) identifier for ecgonine is correctly stated as CHEBI:4743.
The DrugBank identifier for ecgonine is DB01525.
Answer: True
The identifier DB01525 is correctly assigned to ecgonine within the DrugBank database.
The KEGG identifier for ecgonine is C10858.
Answer: True
The KEGG (Kyoto Encyclopedia of Genes and Genomes) identifier assigned to ecgonine is C10858.
The UNII identifier for ecgonine is DX2E9E17AV.
Answer: True
The Unique Ingredient Identifier (UNII) assigned by the U.S. Food and Drug Administration (FDA) for ecgonine is indeed DX2E9E17AV.
The standard InChIKey for ecgonine is PHMBVCPLDPDESM-FKSUSPILSA-N.
Answer: True
The standard InChIKey provided for ecgonine, PHMBVCPLDPDESM-FKSUSPILSA-N, is accurate.
What specific identifier is assigned by the Chemical Abstracts Service (CAS) to ecgonine?
Answer: 481-37-8
The Chemical Abstracts Service (CAS) assigns the unique numerical identifier 481-37-8 to ecgonine.
What is the fundamental purpose of the SMILES notation as applied to ecgonine?
Answer: A textual representation using ASCII strings
SMILES (Simplified Molecular Input Line Entry System) notation provides a method for representing the chemical structure of molecules, such as ecgonine, using a standardized system of short ASCII strings.
From which database is the identifier ChEMBL612017 associated with ecgonine?
Answer: ChEMBL
The identifier ChEMBL612017 for ecgonine is sourced from the ChEMBL database, which curates information on bioactive molecules.
What is the designated PubChem Compound ID (CID) for ecgonine?
Answer: 91460
The PubChem database assigns the Compound ID (CID) 91460 to ecgonine.
What identifier is associated with the European Chemicals Agency (ECHA) for ecgonine?
Answer: ECHA InfoCard: 100.006.879
The European Chemicals Agency (ECHA) assigns the identifier '100.006.879' to ecgonine via its InfoCard system.
What Unique Ingredient Identifier (UNII) is assigned by the U.S. Food and Drug Administration (FDA) to ecgonine?
Answer: UNII: DX2E9E17AV
The U.S. Food and Drug Administration (FDA) assigns the Unique Ingredient Identifier (UNII) DX2E9E17AV to ecgonine.
What is the designated ChemSpider identifier for ecgonine?
Answer: 82586
The ChemSpider database assigns the identifier 82586 to ecgonine.
Which identifier is listed for ecgonine within the U.S. Environmental Protection Agency's CompTox Chemicals Dashboard?
Answer: DTXSID701019899
The CompTox Chemicals Dashboard lists DTXSID701019899 as an identifier for ecgonine.
Within the United States federal legal framework, ecgonine is categorized as a Schedule I controlled substance, signifying a lack of accepted medical utility.
Answer: False
Contrary to the assertion, ecgonine is classified as a Schedule II controlled substance in the United States under the Controlled Substances Act. This classification acknowledges a high potential for abuse while also recognizing accepted medical uses.
In Australia, ecgonine is classified under Schedule 9 of the Standard for the Uniform Scheduling of Medicines and Poisons, designating it as a prohibited substance.
Answer: True
Ecgonine is indeed classified under Schedule 9 in Australia, indicating its status as a prohibited substance.
Ecgonine is classified as a Schedule I controlled substance in Canada.
Answer: False
In Canada, ecgonine is listed under Schedule I of the Controlled Drugs and Substances Act, not Schedule I as a general classification, but specifically within that schedule.
Ecgonine is regulated as a Class F1 narcotic in Brazil.
Answer: True
In Brazil, ecgonine is regulated under the classification of Class F1, designating it as a prohibited narcotic.
What is the legal classification of ecgonine within the jurisdiction of the United Kingdom?
Answer: A Controlled Drug
Within the United Kingdom, ecgonine is legally designated as a Controlled Drug, subjecting its handling to specific regulatory controls.
Under what regulatory classification is ecgonine regulated in Brazil?
Answer: Class F1
In Brazil, ecgonine is subject to regulation under the classification of Class F1, as stipulated by the Brazilian Controlled Drugs and Substances Act.
What is the primary reason cited for ecgonine's classification as a controlled substance in numerous jurisdictions?
Answer: Because it is a precursor and metabolite of cocaine.
Ecgonine is classified as a controlled substance primarily due to its dual role as a metabolite of cocaine and a precursor in its synthesis.
Oxidizing ecgonine produces different products compared to oxidizing tropine.
Answer: False
The source indicates that the oxidation of ecgonine yields the same products as the oxidation of tropine, suggesting similar reaction pathways or structural components susceptible to oxidation.
Heating anhydroecgonine with hydrochloric acid produces tropidine.
Answer: True
The process described involves heating anhydroecgonine with hydrochloric acid, which results in the production of tropidine.
Describe the chemical transformation that ecgonine undergoes when subjected to warming in the presence of alkalis.
Answer: It converts into iso-ecgonine, a dextrorotary stereoisomer.
When ecgonine is warmed with alkalis, it undergoes a transformation into iso-ecgonine, a stereoisomer that exhibits dextrorotary optical activity.
What is the resultant compound when ecgonine undergoes reaction with phosphorus pentachloride (PCl5)?
Answer: It yields anhydroecgonine (C9H13NO2).
The reaction of ecgonine with phosphorus pentachloride (PCl5) results in the formation of anhydroecgonine, which has the chemical formula C9H13NO2.