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Total Categories: 6
The acronym PSSRdb stands for Prokaryotic Simple Sequence Repeats database, indicating its focus on bacterial and archaeal DNA.
Answer: False
The acronym PSSRdb stands for Polymorphic Simple Sequence Repeats database, not Prokaryotic Simple Sequence Repeats database. While it focuses on prokaryotic DNA, the 'P' in PSSRdb refers to 'Polymorphic'.
PSSRdb primarily contains simple sequence repeats that exhibit variation within a population, specifically extracted from eukaryotic genomes.
Answer: False
PSSRdb focuses on polymorphic simple sequence repeats extracted specifically from prokaryotic genomes, not eukaryotic genomes.
The simple sequence repeats in PSSRdb are derived exclusively from single-celled organisms lacking a membrane-bound nucleus, such as bacteria and archaea.
Answer: True
The simple sequence repeats in PSSRdb are indeed extracted exclusively from prokaryotic genomes, which include single-celled organisms like bacteria and archaea that lack a membrane-bound nucleus.
A 'repeated sequence' in DNA refers to a pattern that occurs multiple times in the genome and can vary in length and copy number.
Answer: True
As referenced by the article, a 'repeated sequence' in DNA is defined as a pattern that occurs multiple times in the genome and can vary in length and copy number.
The term 'polymorphic' in PSSRdb's context indicates that the simple sequence repeats are identical across all individuals within a population.
Answer: False
The term 'polymorphic' in PSSRdb's context signifies that the simple sequence repeats exhibit variation among individuals or strains within a population, not that they are identical.
PSSRdb specifically contains simple sequence repeats that are both polymorphic and exclusively found in eukaryotic genomes.
Answer: False
PSSRdb specifically contains polymorphic simple sequence repeats extracted from prokaryotic genomes, not eukaryotic genomes.
The PSSRdb database is a specialized collection of biological data focused on DNA sequences that are both repetitive and show variations within a population.
Answer: True
PSSRdb is indeed a specialized collection of biological data focused on DNA sequences that are both repetitive (simple sequence repeats) and exhibit variations within a population (polymorphic).
What is the full name represented by the acronym PSSRdb?
Answer: Polymorphic Simple Sequence Repeats database
The acronym PSSRdb stands for Polymorphic Simple Sequence Repeats database.
What is the primary content or focus of the PSSRdb database?
Answer: Polymorphic simple sequence repeats from prokaryotic genomes.
The PSSRdb database primarily contains polymorphic simple sequence repeats (SSRs) extracted from prokaryotic genomes.
From which type of organisms are the simple sequence repeats in PSSRdb specifically extracted?
Answer: Prokaryotic genomes
The simple sequence repeats stored in PSSRdb are extracted specifically from prokaryotic genomes.
What does the term 'polymorphic' signify in the context of the PSSRdb database's content?
Answer: The sequences exhibit variation among individuals or strains.
In the context of PSSRdb, 'polymorphic' signifies that the simple sequence repeats exhibit variation among individuals or strains within a population.
How does PSSRdb specifically characterize the simple sequence repeats it contains?
Answer: As polymorphic and extracted from prokaryotic genomes.
PSSRdb specifically characterizes the simple sequence repeats it contains as 'polymorphic' and as being 'extracted from prokaryotic genomes.'
What is the general definition of a 'repeated sequence' in the context of DNA, as referenced by the article?
Answer: A pattern of DNA that occurs multiple times in the genome, which can vary in length and copy number.
A 'repeated sequence' in the context of DNA refers to a pattern that occurs multiple times in the genome and can vary in length and copy number, playing various roles in genome structure and function.
What does the term 'simple sequence repeats' (SSRs) refer to in molecular biology?
Answer: Short, tandemly repeated DNA sequences.
In molecular biology, 'simple sequence repeats' (SSRs) refer to short, tandemly repeated DNA sequences.
Users can access the PSSRdb database online through a website hosted by the National Institutes of Health.
Answer: False
Users can access the PSSRdb database online via its dedicated website, http://www.cdfd.org.in/PSSRdb/, which is associated with the Centre for DNA Fingerprinting and Diagnostics, not the National Institutes of Health.
The primary citation describes PSSRdb as a hierarchical database, organizing data in a tree-like structure.
Answer: False
The primary citation describes PSSRdb as a relational database, which organizes data into tables with defined relationships, rather than a hierarchical database.
PSSRdb contributes to computational biology by offering a structured collection of genetic data, aiding in the development of analytical tools and algorithms.
Answer: True
PSSRdb contributes to computational biology by providing a structured and accessible collection of genetic data, which is essential for the development of analytical tools and algorithms.
The description of PSSRdb as a 'relational database' implies that its data is organized into tables with defined relationships, facilitating efficient querying.
Answer: True
The description of PSSRdb as a 'relational database' indeed implies that its data is organized into tables with defined relationships, which facilitates efficient querying, management, and integration of information.
The PSSRdb website primarily serves as an archive for historical genetic data, with limited interactive features.
Answer: False
The PSSRdb website provides an interface for searching, browsing, and downloading current polymorphic simple sequence repeat data, indicating it is an active resource with interactive features, not primarily an archive for historical data.
The PSSRdb website allows researchers to browse or download data, making its resources readily available.
Answer: True
The PSSRdb website, http://www.cdfd.org.in/PSSRdb/, provides an interface for researchers to browse or download data, making its resources readily available.
Where can users access the PSSRdb database online?
Answer: http://www.cdfd.org.in/PSSRdb/
Users can access the PSSRdb database online via its dedicated website, http://www.cdfd.org.in/PSSRdb/.
What is the nature of the database, as implied by its full name and description in its primary citation?
Answer: A relational database
The database is described as a 'Polymorphic Simple Sequence Repeats database,' and its primary citation refers to it as a 'relational database.'
How does the PSSRdb contribute to the broader field of computational biology?
Answer: By providing a structured and accessible collection of genetic data for analytical tools.
PSSRdb contributes to computational biology by providing a structured and accessible collection of genetic data, which is essential for the development of analytical tools and algorithms.
What is the significance of a database being described as 'relational' in the context of PSSRdb's functionality?
Answer: It implies data is organized into tables with defined relationships for efficient querying.
Being described as 'relational' signifies that PSSRdb's data is organized into tables with defined relationships, allowing for efficient querying, management, and integration of complex biological information.
How does the provided website for PSSRdb facilitate access and utility for researchers?
Answer: It provides an interface for searching, browsing, and downloading the polymorphic simple sequence repeat data.
The PSSRdb website facilitates access and utility for researchers by providing an interface for searching, browsing, and downloading the polymorphic simple sequence repeat data.
The Centre for DNA Fingerprinting and Diagnostics is the research institution associated with the development and maintenance of the PSSRdb database.
Answer: True
The Centre for DNA Fingerprinting and Diagnostics is explicitly stated as the research institution associated with the development and maintenance of the PSSRdb database.
The PSSRdb database was developed by the Laboratory of Molecular Genetics India, specializing in genetic analysis.
Answer: False
The PSSRdb database was developed by the Laboratory of Computational Biology India, not the Laboratory of Molecular Genetics India.
Pankaj Kumar is recognized as a primary author for the foundational publication describing the PSSRdb database.
Answer: True
Pankaj Kumar is indeed listed as a primary author for the foundational publication (Kumar & al. (2011)) that describes the PSSRdb database.
The PSSRdb database became publicly available for researchers in 2011, coinciding with its primary scientific citation.
Answer: False
The PSSRdb database was initially released to the public in 2010, while its primary scientific citation was published in January 2011.
Chaitanya Pasumarthy S and Nagarajaram Hampapathalu A are listed as co-authors alongside Pankaj Kumar in the PSSRdb primary citation.
Answer: True
Chaitanya Pasumarthy S and Nagarajaram Hampapathalu A are explicitly listed as co-authors alongside Pankaj Kumar in the primary citation for PSSRdb.
The Centre for DNA Fingerprinting and Diagnostics provided the institutional support and resources for PSSRdb's development and hosting.
Answer: True
The Centre for DNA Fingerprinting and Diagnostics is the research center associated with PSSRdb, providing the institutional support, resources, and scientific environment for its development and hosting.
Computational biology was crucial in the creation and management of PSSRdb, as it involves using computers to analyze biological data.
Answer: True
The Laboratory of Computational Biology India developed PSSRdb, highlighting that computational biology, which involves using computers to analyze biological data, was crucial in its creation and management.
Lead authors like Pankaj Kumar are typically responsible for only the final review of bioinformatics resources.
Answer: False
Lead authors like Pankaj Kumar are typically instrumental in the conceptualization, development, and scientific documentation of bioinformatics resources, not solely responsible for final review.
Which research center is associated with the development and maintenance of PSSRdb?
Answer: Centre for DNA Fingerprinting and Diagnostics
The Centre for DNA Fingerprinting and Diagnostics is the research center associated with the development and maintenance of PSSRdb.
Which specific laboratory was involved in the creation of the PSSRdb database?
Answer: Laboratory of Computational Biology India
The PSSRdb database was developed by the Laboratory of Computational Biology India.
Who is listed as a primary author for the PSSRdb database's foundational publication?
Answer: Pankaj Kumar
Pankaj Kumar is listed as a primary author for the PSSRdb database's foundational publication.
When was the PSSRdb database initially released to the public?
Answer: 2010
The PSSRdb database was initially released to the public in 2010.
Who are the co-authors listed alongside Pankaj Kumar in the primary citation for PSSRdb?
Answer: Chaitanya Pasumarthy S and Nagarajaram Hampapathalu A
Chaitanya Pasumarthy S and Nagarajaram Hampapathalu A are listed as co-authors alongside Pankaj Kumar in the primary citation for PSSRdb.
What is the primary function of the Centre for DNA Fingerprinting and Diagnostics in relation to PSSRdb's existence?
Answer: To serve as the institutional support, resources, and scientific environment for its development and hosting.
The Centre for DNA Fingerprinting and Diagnostics serves as the research center associated with PSSRdb, providing the institutional support, resources, and scientific environment necessary for its development, hosting, and ongoing availability.
What is the primary role of lead authors like Pankaj Kumar in the context of bioinformatics resources?
Answer: Instrumental in the conceptualization, development, and scientific documentation.
Lead authors like Pankaj Kumar are typically instrumental in the conceptualization, development, and scientific documentation of bioinformatics resources.
What kind of institution is the Centre for DNA Fingerprinting and Diagnostics, based on its association with PSSRdb?
Answer: A research institution focused on advanced molecular biology techniques.
Based on its association with PSSRdb, the Centre for DNA Fingerprinting and Diagnostics is a research institution that typically focuses on advanced molecular biology techniques, including genetic analysis and bioinformatics.
The primary scientific citation for PSSRdb is Kumar & al. (2011), which formally introduces the database to the scientific community.
Answer: True
Kumar & al. (2011) is indeed identified as the primary scientific citation for PSSRdb, serving to formally introduce and describe the database to the scientific community.
The primary citation for PSSRdb was published in the journal *Science*, a leading multidisciplinary scientific journal.
Answer: False
The primary citation for PSSRdb was published in the journal *Nucleic Acids Research*, not *Science*.
The PSSRdb primary citation was published in Volume 39 of *Nucleic Acids Research*, within a special 'Database issue'.
Answer: True
The primary citation for PSSRdb was indeed published in Volume 39 of *Nucleic Acids Research*, specifically within a 'Database issue'.
The article describing PSSRdb can be found on pages D601-5 of *Nucleic Acids Research*.
Answer: True
The article describing PSSRdb is indeed located on pages D601-5 of *Nucleic Acids Research*.
The journal article describing PSSRdb was published in the United States.
Answer: False
The journal article describing PSSRdb was published in England, not the United States.
The DOI for the primary citation of PSSRdb is 10.1093/nar/gkq1198, providing a persistent link to the electronic document.
Answer: True
The DOI for the primary citation of PSSRdb is indeed 10.1093/nar/gkq1198, which provides a persistent and reliable link to the electronic document.
The PMC identifier 3013739 indicates that the PSSRdb article is freely accessible through PubMed Central.
Answer: True
The PMC identifier 3013739 indicates that the PSSRdb article is freely accessible through PubMed Central, a free full-text archive of biomedical and life sciences journal literature.
The PMID for the primary citation of PSSRdb is 21112874, which is a unique identification number in the PubMed database.
Answer: True
The PMID for the primary citation of PSSRdb is indeed 21112874, serving as a unique identification number within the PubMed database.
The primary citation for PSSRdb was published in December 2010, shortly after the database's initial release.
Answer: False
The primary citation for PSSRdb was published in January 2011, not December 2010, although the database was released in 2010.
Publication in a 'Database issue' of *Nucleic Acids Research* signifies PSSRdb's recognition as a valuable bioinformatics resource.
Answer: True
Publication in a 'Database issue' of *Nucleic Acids Research* specifically signifies PSSRdb's recognition as a valuable and established bioinformatics resource, as such issues are dedicated to showcasing new and updated biological databases.
What is the primary scientific citation that describes the PSSRdb database?
Answer: Kumar & al. (2011)
The primary scientific citation that describes the PSSRdb database is Kumar & al. (2011).
What is the name of the journal in which the primary citation for PSSRdb was published?
Answer: Nucleic Acids Research
The primary citation for PSSRdb was published in the journal *Nucleic Acids Research*.
What is the volume and specific issue information for the primary citation of PSSRdb?
Answer: Volume 39, 'Database issue'
The primary citation for PSSRdb was published in Volume 39, specifically within a 'Database issue' of *Nucleic Acids Research*.
What are the page numbers associated with the primary citation for PSSRdb?
Answer: D601-5
The primary citation for PSSRdb can be found on pages D601-5 of *Nucleic Acids Research*.
What is the country of publication for the journal article describing PSSRdb?
Answer: England
The journal article describing PSSRdb was published in England.
What is the DOI (Digital Object Identifier) for the primary citation of PSSRdb?
Answer: 10.1093/nar/gkq1198
The DOI for the primary citation of PSSRdb is 10.1093/nar/gkq1198.
What is the PMC (PubMed Central) identifier for the primary citation of PSSRdb?
Answer: 3013739
The PMC (PubMed Central) identifier for the primary citation of PSSRdb is 3013739.
What is the PMID (PubMed Identifier) for the primary citation of PSSRdb?
Answer: 21112874
The PMID (PubMed Identifier) for the primary citation of PSSRdb is 21112874.
What month and year was the primary citation for PSSRdb published?
Answer: January 2011
The primary citation for PSSRdb was published in January 2011.
What is the significance of the 'Database issue' in which the PSSRdb primary citation was published for its recognition in the scientific community?
Answer: It signifies its recognition as a valuable and established bioinformatics resource.
The publication of the PSSRdb primary citation in a 'Database issue' of *Nucleic Acids Research* signifies its recognition as a valuable and established bioinformatics resource, as such issues are dedicated to showcasing new and updated biological databases.
Extracting simple sequence repeats from prokaryotic genomes is significant for PSSRdb because these sequences serve as genetic markers for studying diversity and evolutionary relationships in prokaryotic species.
Answer: True
Simple sequence repeats from prokaryotic genomes are significant for PSSRdb because they serve as valuable genetic markers for studying genetic diversity, population structure, and evolutionary relationships within prokaryotic species.
Researchers can utilize PSSRdb to find data on polymorphic simple sequence repeats from eukaryotic genomes, which are valuable genetic markers.
Answer: False
Researchers can utilize PSSRdb to find data on polymorphic simple sequence repeats from prokaryotic genomes, not eukaryotic genomes.
PSSRdb focuses on polymorphic simple sequence repeats because these variations are less informative for genetic studies compared to conserved repeats.
Answer: False
PSSRdb focuses on polymorphic simple sequence repeats precisely because these variations are highly informative for genetic studies, serving as powerful genetic markers to distinguish strains and track evolutionary lineages.
What is the significance of extracting simple sequence repeats specifically from prokaryotic genomes for a database like PSSRdb?
Answer: These sequences serve as valuable genetic markers for studying diversity and evolution in prokaryotic species.
Extracting simple sequence repeats from prokaryotic genomes for PSSRdb is significant because these sequences serve as valuable genetic markers for studying genetic diversity, population structure, and evolutionary relationships within prokaryotic species.
What kind of biological information can researchers expect to find within the PSSRdb that is useful for genetic studies?
Answer: Polymorphic simple sequence repeats (SSRs) specifically derived from prokaryotic genomes.
Researchers can expect to find data on polymorphic simple sequence repeats (SSRs) specifically derived from prokaryotic genomes within the PSSRdb, which are highly valuable for genetic studies.
Why might a database specifically focus on 'polymorphic' simple sequence repeats rather than all simple sequence repeats?
Answer: Polymorphic repeats are highly informative for genetic studies, distinguishing strains and tracking lineages.
A database like PSSRdb focuses on 'polymorphic' simple sequence repeats because these variations are highly informative for genetic studies, enabling the distinction between different strains or individuals of prokaryotes and the tracking of evolutionary lineages.
The PSSRdb is visually represented in its infobox by a specific logo depicting a DNA double helix.
Answer: False
The PSSRdb is visually represented in its infobox by a generic image file named 'Database.png,' not a specific logo depicting a DNA double helix.
The Wikipedia article about PSSRdb is classified as a 'featured article,' indicating comprehensive coverage and high quality.
Answer: False
The Wikipedia article about PSSRdb is classified as a 'stub,' meaning it is a short and incomplete article, not a 'featured article.'
The article's stub classification indicates that PSSRdb belongs to the broader category of 'Genomic sequencing projects'.
Answer: False
The article's stub classification indicates that PSSRdb belongs to the broader category of 'Biological database-related' articles, not 'Genomic sequencing projects'.
The inclusion of 'sequence repeats' in the 'See also' section suggests that PSSRdb is a general database covering all types of DNA repeats.
Answer: False
The inclusion of 'sequence repeats' in the 'See also' section suggests that PSSRdb is a specialized database focusing on a particular type of sequence repeat, requiring foundational understanding of general repeats, rather than covering all types.
The 2010 release date of PSSRdb indicates its establishment during a period of declining interest in genomic sequencing technologies.
Answer: False
The 2010 release date of PSSRdb indicates its establishment during a period of rapid growth in genomic sequencing technologies and an increasing need for specialized computational tools and databases.
What type of visual representation is used for the PSSRdb in its infobox?
Answer: A generic icon symbolizing a database, named 'Database.png'.
The PSSRdb is visually represented in its infobox by an image file named 'Database.png,' which serves as a generic icon symbolizing a database.
What is the overall status of the Wikipedia article about the Polymorphic Simple Sequence Repeats database?
Answer: Stub
The Wikipedia article about the Polymorphic Simple Sequence Repeats database is identified as a 'stub,' meaning it is a short and incomplete article.
What is the broader category of biological databases that PSSRdb belongs to, as indicated by the article's stub classification?
Answer: Biological database-related articles
The article's stub classification indicates that PSSRdb belongs to the broader category of 'Biological database-related' articles.
What does the inclusion of 'sequence repeats' in the 'See also' section suggest about the scope of PSSRdb?
Answer: PSSRdb is a specialized database focusing on a particular type of sequence repeat, requiring foundational understanding of general repeats.
The inclusion of 'sequence repeats' in the 'See also' section suggests that PSSRdb is a specialized database focusing on a particular type of sequence repeat, implying that a foundational understanding of general sequence repeats is necessary.
How does the release date of 2010 for PSSRdb inform its historical context within bioinformatics?
Answer: It places it during a time of rapid growth in genomic sequencing technologies and the increasing need for specialized tools.
The release date of 2010 places PSSRdb within a historical context of rapid growth in genomic sequencing technologies and the increasing need for specialized computational tools and databases to manage and analyze biological data.
What is the significance of the 2010 release date for PSSRdb in the context of bioinformatics?
Answer: It places the database's establishment during a time of rapid growth in genomic sequencing technologies.
The 2010 release date for PSSRdb is significant as it places the database's establishment during a period of rapid growth in genomic sequencing technologies and the increasing need for specialized computational tools and databases.