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The Cervical Spine: Pillars of the Neck

An in-depth, educational guide to the cervical vertebrae, exploring their structure, function, clinical significance, and anatomical landmarks.

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Introduction

Defining the Neck's Vertebrae

In tetrapods, the cervical vertebrae constitute the segment of the vertebral column located in the neck, situated immediately inferior to the skull. In mammals, these are followed by the truncal vertebrae, which are further divided into thoracic and lumbar regions. While most mammals possess seven cervical vertebrae, notable exceptions exist, such as the manatee with six, and the two-toed and three-toed sloths with five to six, and nine, respectively.[2][3] This article focuses specifically on the anatomy of human cervical vertebrae.[1]

Evolutionary Context

In sauropsid species (reptiles and birds), the cervical vertebrae often bear cervical ribs. These ribs are substantial in lizards and saurischian dinosaurs but are reduced and fused to the vertebrae in birds. The transverse processes of mammalian cervical vertebrae are considered homologous to the cervical ribs found in other amniotes.[1]

Structure

General Characteristics (C3-C6)

The third through sixth cervical vertebrae share common features. Their bodies are relatively small, being wider transversely than they are deep anteroposteriorly. The anterior and posterior surfaces are flattened and of equal depth. The inferior border of the body projects downward, slightly overlapping the vertebra below. The superior surface is transversely concave with a projecting lip on each side, while the inferior surface is concave from front to back and convex side to side, featuring shallow lateral concavities for articulation.

Arches and Processes

The pedicles project laterally and backward, attaching midway up the body. The laminae are narrow and thinner superiorly, forming a large, triangular vertebral foramen. The spinous processes are short and typically bifid, serving as attachment points for the nuchal ligament. Articular processes are fused into pillars, with superior facets facing backward, upward, and medially, and inferior facets facing forward, downward, and laterally.

Transverse Foramen and Arteries

A defining characteristic of human cervical vertebrae (C3-C7) is the presence of a transverse foramen within each transverse process. This opening serves as a crucial passageway for the vertebral artery, vertebral veins, and sympathetic nerves. The transverse process itself consists of anterior and posterior parts, joined by a bone bar that creates a sulcus for the spinal nerve. The anterior part is homologous to a rib, while the posterior part is the true transverse process.

Atlas & Axis

The Atlas (C1)

The atlas, or C1, is the uppermost cervical vertebra and forms the primary articulation with the skull. It is unique in its ring-like structure, lacking a vertebral body and spinous process. It comprises an anterior arch, a posterior arch, and two lateral masses, which bear the articular facets for the occipital condyles.

The Axis (C2)

The axis, or C2, facilitates the rotational movement of the head. Its most distinctive feature is the odontoid process (dens) which projects superiorly from the body to articulate with the atlas. The body of the axis is deeper anteriorly and overlaps the third cervical vertebra.

Vertebra Prominens (C7)

Identifying C7

The seventh cervical vertebra, known as the vertebra prominens, is characterized by its exceptionally long and prominent spinous process, which is readily palpable externally. This process is typically thick, nearly horizontal, and not bifurcated, serving as a key attachment point for the nuchal ligament. While usually the most prominent, variations exist where C6 or T1 may be more prominent.

Potential Anomalies

C7's transverse processes are notably large. The transverse foramina may vary in size, sometimes being absent or double, and occasionally do not transmit the vertebral artery. A significant anomaly is the occasional development of a cervical rib from the anterior root of the transverse process. These ribs, though often small, can compress adjacent neurovascular structures, potentially leading to thoracic outlet syndrome symptoms like pain, numbness, or weakness in the upper limb.[8]

Function

Head Movement: The "Yes" Joint

The primary movement of nodding the head, akin to saying "yes," occurs predominantly at the atlanto-occipital joint, formed between the atlas (C1) and the occipital bone of the skull. While some flexion and extension of the cervical spine itself contribute, this articulation is the main driver of this motion.

Head Rotation: The "No" Joint

The side-to-side rotation of the head, resembling a "no" motion, is largely facilitated by the atlanto-axial joint between the atlas (C1) and the axis (C2). The unique structure of this joint, particularly the odontoid process of the axis, allows for extensive rotation, enabling the head to turn significantly.

Clinical Significance

Degenerative Changes

Cervical degenerative changes, including spondylosis, intervertebral disc stenosis, and osteophyte formation, are commonly assessed using radiographic imaging. A grading system (0-4) quantifies these changes, ranging from no abnormalities to severe disc space narrowing and vertebral end-plate sclerosis.[5][6][7]

Trauma and Injury

While injuries are frequent at the C2 level, significant neurological damage is uncommon. However, the C4 and C5 levels experience the highest incidence of cervical spine trauma. Severe injuries can lead to profound disability, including paralysis and respiratory failure. Common fractures like odontoid and hangman's fractures are often managed with immobilization devices such as cervical collars or halo braces.[8]

Imaging and Assessment

Medical imaging, particularly X-rays and CT scans, utilizes specific annotations known as "cervical lines." Deviations from these lines can indicate cervical fractures, spondylolisthesis, or ligamentous injuries. The Canadian C-Spine Rule (CCR) provides a clinical guideline for determining the necessity of radiological imaging in patients with suspected cervical spine trauma.[9]

Anatomical Landmarks

Key Vertebral Levels

The vertebral column serves as a critical reference point in human anatomy. Specific cervical vertebral levels correspond to important anatomical structures:

  • C1: Base of the nose, hard palate.
  • C2: Teeth of a closed mouth.
  • C3: Mandible, hyoid bone.
  • C4: Bifurcation of the common carotid artery.
  • C4-C5: Thyroid cartilage.
  • C6-C7: Cricoid cartilage.
  • C6: Level where the esophagus becomes continuous with the laryngopharynx, and the larynx with the trachea. The carotid pulse is also palpable against the C6 transverse process.

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References

References

  1.  MedicalMnemonics.com: 3548
A full list of references for this article are available at the Cervical vertebrae Wikipedia page

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Important Notice

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